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辣椒粉粉尘诱导大鼠实验性纤维性细支气管肺泡炎的病因学

The aetiology of experimental fibrosing alveobronchiolitis induced in rats by paprika dust.

作者信息

Tátrai E, Ungváry G

机构信息

National Institute of Occupational Health, Budapest, Hungary.

出版信息

Br J Ind Med. 1992 Jul;49(7):494-8.

PMID:1637709
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1039271/
Abstract

The effect of a single intratracheal dose of respirable paprika (Hungarian) dust, paprika dust extract, and cellulose dust on the lungs of rats was examined sequentially one and three months after a treatment. Treatment with respirable paprika and cellulose dusts resulted in alveobronchiolitis at the end of the first month and fibrotic changes at the end of the third month. As the extract of paprika dust caused no histopathological alterations, it is assumed that the high cellulose content of paprika was responsible for the histological reactions.

摘要

在对大鼠进行治疗后的1个月和3个月时,依次检查了经气管内单次给予可吸入的辣椒粉(匈牙利产)粉尘、辣椒粉粉尘提取物和纤维素粉尘对大鼠肺部的影响。给予可吸入的辣椒粉和纤维素粉尘治疗后,在第1个月末导致细支气管肺泡炎,在第3个月末导致纤维化改变。由于辣椒粉粉尘提取物未引起组织病理学改变,推测辣椒粉中高纤维素含量是造成这些组织学反应的原因。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8e1a/1039271/9a1c17a8975a/brjindmed00019-0043-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8e1a/1039271/c4c37c8fe829/brjindmed00019-0041-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8e1a/1039271/7e2a52035b58/brjindmed00019-0041-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8e1a/1039271/6c269439f39d/brjindmed00019-0042-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8e1a/1039271/fbddca38a715/brjindmed00019-0042-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8e1a/1039271/3b4ca4e095aa/brjindmed00019-0043-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8e1a/1039271/9a1c17a8975a/brjindmed00019-0043-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8e1a/1039271/c4c37c8fe829/brjindmed00019-0041-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8e1a/1039271/7e2a52035b58/brjindmed00019-0041-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8e1a/1039271/6c269439f39d/brjindmed00019-0042-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8e1a/1039271/fbddca38a715/brjindmed00019-0042-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8e1a/1039271/3b4ca4e095aa/brjindmed00019-0043-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8e1a/1039271/9a1c17a8975a/brjindmed00019-0043-b.jpg

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Asthma and other symptoms in cinnamon workers.肉桂加工工人中的哮喘及其他症状。
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Symptoms among chilli grinders.辣椒研磨工中的症状。
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