Tátrai E, Adamis Z, Ungváry G
Department of Pathology, National Institute of Occupational Health, Budapest, Hungary.
Indian J Med Res. 1995 Dec;102:287-92.
The histopathological effect of a single intratracheal dose of respirable cinnamon dust, cinnamon dust extract, and cellulose dust on the lungs of rats was studied sequentially one, seven days and one month after treatment. Exposure to respirable cinnamon and cellulose dusts resulted in alveobronchiolitis at the end of the first and seventh day, and fibrotic changes by the end of the first month. As the extract of cinnamon dust caused no histopathological alterations, it is assumed that the cellulose content of cinnamon dust was responsible for the histological reactions.
研究了单次气管内给予可吸入肉桂粉尘、肉桂粉尘提取物和纤维素粉尘对大鼠肺部的组织病理学影响，分别在处理后1天、7天和1个月进行连续观察。暴露于可吸入肉桂粉尘和纤维素粉尘后，在第1天和第7天结束时出现肺泡细支气管炎，在第1个月结束时出现纤维化改变。由于肉桂粉尘提取物未引起组织病理学改变，推测肉桂粉尘中的纤维素成分是导致组织学反应的原因。
