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核糖体对正确阅读框的识别。

Recognition of correct reading frame by the ribosome.

作者信息

Trifonov E N

机构信息

Department of Structural Biology, Weizmann Institute of Science, Rehovot, Israel.

出版信息

Biochimie. 1992 Apr;74(4):357-62. doi: 10.1016/0300-9084(92)90113-s.

DOI:10.1016/0300-9084(92)90113-s
PMID:1637861
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7131330/
Abstract

The translation frame-monitoring mechanism has been suggested earlier, based on transient complementary contacts, between mRNA and rRNA. Recent studies related to the frame-monitoring mechanism are reviewed. The mechanism is well supported by both new experimental and sequence analysis data. Experiments are suggested for further elucidation of the structural details of the mRNA-rRNA interaction in the ribosome.

摘要

翻译框架监测机制早前已基于mRNA与rRNA之间的瞬时互补接触被提出。本文综述了近期与该框架监测机制相关的研究。新的实验数据和序列分析数据均有力支持了这一机制。建议开展实验以进一步阐明核糖体中mRNA-rRNA相互作用的结构细节。

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本文引用的文献

1
AN ESTIMATE OF THE SIZE OF THE RIBOSOMAL SITE FOR MESSENGER RNA BINDING.信使核糖核酸结合的核糖体位点大小的估计
Proc Natl Acad Sci U S A. 1964 May;51(5):834-9. doi: 10.1073/pnas.51.5.834.
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Localization of 5' and 3' ends of the ribosome-bound segment of template polynucleotides by immune electron microscopy.
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3
Covalent crosslinking of tRNA1Val to 16S RNA at the ribosomal P site: identification of crosslinked residues.tRNA1Val在核糖体P位点与16S RNA的共价交联：交联残基的鉴定。
Proc Natl Acad Sci U S A. 1982 Sep;79(18):5450-4. doi: 10.1073/pnas.79.18.5450.
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Partial mRNA sequences for human A alpha, B beta, and gamma fibrinogen chains: evolutionary and functional implications.人αA、βB和γ纤维蛋白原链的部分mRNA序列：进化及功能意义
Proc Natl Acad Sci U S A. 1983 Jul;80(13):3953-7. doi: 10.1073/pnas.80.13.3953.
5
High resolution localization of the tRNA anticodon interaction site on the Escherichia coli 30 S ribosomal subunit.大肠杆菌30S核糖体亚基上tRNA反密码子相互作用位点的高分辨率定位。
J Biol Chem. 1984 Aug 25;259(16):10493-8.
6
Sequence-dependent variations of B-DNA structure and protein-DNA recognition.B-DNA结构和蛋白质-DNA识别的序列依赖性变异
Cold Spring Harb Symp Quant Biol. 1983;47 Pt 1:271-8. doi: 10.1101/sqb.1983.047.01.032.
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Translational initiation in prokaryotes.原核生物中的翻译起始
Annu Rev Microbiol. 1981;35:365-403. doi: 10.1146/annurev.mi.35.100181.002053.
8
The 3'-terminal sequence of Escherichia coli 16S ribosomal RNA: complementarity to nonsense triplets and ribosome binding sites.大肠杆菌16S核糖体RNA的3'末端序列：与无义三联体及核糖体结合位点的互补性
Proc Natl Acad Sci U S A. 1974 Apr;71(4):1342-6. doi: 10.1073/pnas.71.4.1342.
9
Conservation of RNA sequence and cross-linking ability in ribosomes from a higher eukaryote: photochemical cross-linking of the anticodon of P site bound tRNA to the penultimate cytidine of the UACACACG sequence in Artemia salina 18S rRNA.高等真核生物核糖体中RNA序列和交联能力的保守性：卤虫18S rRNA中与P位点结合的tRNA反密码子与UACACACG序列倒数第二个胞苷的光化学交联
Biochemistry. 1985 Jun 18;24(13):3233-9. doi: 10.1021/bi00334a024.
10
Structure of ribosome-bound messenger RNA as revealed by enzymatic accessibility studies.通过酶可及性研究揭示的核糖体结合信使核糖核酸的结构
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