Trifonov E N
Department of Structural Biology, Weizmann Institute of Science, Rehovot, Israel.
Biochimie. 1992 Apr;74(4):357-62. doi: 10.1016/0300-9084(92)90113-s.
The translation frame-monitoring mechanism has been suggested earlier, based on transient complementary contacts, between mRNA and rRNA. Recent studies related to the frame-monitoring mechanism are reviewed. The mechanism is well supported by both new experimental and sequence analysis data. Experiments are suggested for further elucidation of the structural details of the mRNA-rRNA interaction in the ribosome.
翻译框架监测机制早前已基于mRNA与rRNA之间的瞬时互补接触被提出。本文综述了近期与该框架监测机制相关的研究。新的实验数据和序列分析数据均有力支持了这一机制。建议开展实验以进一步阐明核糖体中mRNA-rRNA相互作用的结构细节。