Pissuwan Dakrong, Valenzuela Stella M, Cortie Michael B
Institute for Nanoscale Technology, University of Technology Sydney, Broadway NSW 2007, Australia.
Trends Biotechnol. 2006 Feb;24(2):62-7. doi: 10.1016/j.tibtech.2005.12.004. Epub 2005 Dec 27.
Nanoparticles of gold, which are in the size range 10-100 nm, undergo a plasmon resonance with light. This is a process whereby the electrons of the gold resonate in response to incoming radiation causing them to both absorb and scatter light. This effect can be harnessed to either destroy tissue by local heating or release payload molecules of therapeutic importance. Gold nanoparticles can also be conjugated to biologically active moieties, providing possibilities for targeting to particular tissues. Here, we review the progress made in the exploitation of the plasmon resonance of gold nanoparticles in photo-thermal therapeutic medicine.
尺寸在10至100纳米范围内的金纳米颗粒会与光发生等离子体共振。这是一个过程,在此过程中,金的电子会因入射辐射而共振,导致它们吸收和散射光。这种效应可用于通过局部加热破坏组织或释放具有治疗重要性的负载分子。金纳米颗粒还可以与生物活性部分结合,为靶向特定组织提供了可能性。在这里,我们综述了在光热治疗医学中利用金纳米颗粒的等离子体共振所取得的进展。