Engler Marguerite M, Engler Mary B
Dept. of Physiological Nursing, University of California-San Francisco, 2 Koret Way, San Francisco, CA 94143-0610, USA.
J Cardiovasc Nurs. 2006 Jan-Feb;21(1):17-24, quiz 25-6. doi: 10.1097/00005082-200601000-00005.
Dietary omega-3 polyunsaturated fatty acids, eicosapentaenoic and docosahexaenoic acids, play an important role in cardiovascular health and disease. Clinical trials provide substantial evidence to support current dietary recommendations for omega-3 fatty acids in cardiovascular disease management. The cardioprotective benefits of omega-3 fatty acids may be attributed to multiple physiological effects on lipids, blood pressure, vascular function, cardiac rhythms, platelet function, and inflammatory responses. The metabolism of omega-3 fatty acids, physiological effects, and clinical considerations with current dietary recommendations and sources of omega-3 fatty acids are presented.
膳食中的ω-3多不饱和脂肪酸，即二十碳五烯酸和二十二碳六烯酸，在心血管健康与疾病中发挥着重要作用。临床试验提供了大量证据，支持当前关于ω-3脂肪酸在心血管疾病管理中的膳食建议。ω-3脂肪酸的心脏保护益处可能归因于对脂质、血压、血管功能、心律、血小板功能和炎症反应的多种生理作用。本文介绍了ω-3脂肪酸的代谢、生理作用，以及当前膳食建议和ω-3脂肪酸来源的临床考量。
