Schwalfenberg Gerry
Department of Family Practice, Misericordia Hospital, Edmonton, Alta.
Can Fam Physician. 2006 Jun;52(6):734-40.
To examine evidence for the role of omega-3 fatty acids in cardiovascular disease.
PubMed was searched for articles on the role of omega-3 fatty acids in cardiovascular disease. Level I and II evidence indicates that omega-3 fatty acids are beneficial in improving cardiovascular outcomes.
Dietary intake of omega-3 fatty acids has declined by 80% during the last 100 years, while intake of omega-6 fatty acids has greatly increased. Omega-3 fatty acids are cardioprotective mainly due to beneficial effects on arrhythmias, atherosclerosis, inflammation, and thrombosis. There is also evidence that they improve endothelial function, lower blood pressure, and significantly lower triglycerides.
There is good evidence in the literature that increasing intake of omega-3 fatty acids improves cardiac outcomes. Physicians need to integrate dietary recommendations for consumption of omega-3 fatty acids into their usual cardiovascular care.
研究ω-3脂肪酸在心血管疾病中作用的证据。
检索PubMed上关于ω-3脂肪酸在心血管疾病中作用的文章。一级和二级证据表明，ω-3脂肪酸有助于改善心血管结局。
在过去100年中，ω-3脂肪酸的膳食摄入量下降了80%，而ω-6脂肪酸的摄入量大幅增加。ω-3脂肪酸具有心脏保护作用，主要是因为它对心律失常、动脉粥样硬化、炎症和血栓形成具有有益影响。也有证据表明，它们可改善内皮功能、降低血压并显著降低甘油三酯。
文献中有充分证据表明，增加ω-3脂肪酸的摄入量可改善心脏结局。医生需要将ω-3脂肪酸摄入的饮食建议纳入其常规心血管护理中。
