Forgács Zsolt, Somosy Zoltán, Kubinyi Györgyi, Bakos József, Hudák Aranka, Surján András, Thuróczy György
Department of Molecular and Cell Biology, National Institute of Chemical Safety, H-1096 Budapest, Nagyvárad tér 2., Hungary.
Reprod Toxicol. 2006 Jul;22(1):111-7. doi: 10.1016/j.reprotox.2005.12.003. Epub 2006 Jan 24.
The aim of our study was to evaluate the possible effects of whole-body 1800 MHz GSM-like microwave exposure on male reproduction. After repeated exposure of mice to microwaves at 0.018-0.023 W/kg whole-body specific energy absorption rate (SAR) an elevated serum testosterone level was measured, but no microwave exposure related histopathological alteration could be detected in the reproductive organs. The in vitro steroidogenic response of 48 h Leydig cell cultures obtained from exposed animals did not differ from the controls, suggesting that Leydig cells were not the primary targets of the applied microwave exposure or direct action of microwaves on Leydig cells was temporary only. In exposed animals the red blood cell count and volume of packed red cells were also increased. Further investigations are required to clarify the mechanism of action of the applied microwave exposure on male mice, as well as to establish the biological significance of the observed phenomena.
我们研究的目的是评估全身1800兆赫类似全球移动通信系统（GSM）的微波辐射对雄性生殖可能产生的影响。在将小鼠反复暴露于全身比吸收率（SAR）为0.018 - 0.023瓦/千克的微波环境后，检测到血清睾酮水平升高，但在生殖器官中未检测到与微波辐射相关的组织病理学改变。从暴露动物获取的48小时睾丸间质细胞培养物的体外类固醇生成反应与对照组无差异，这表明睾丸间质细胞不是所施加微波辐射的主要靶点，或者微波对睾丸间质细胞的直接作用只是暂时的。在暴露动物中，红细胞计数和红细胞压积也有所增加。需要进一步研究以阐明所施加的微波辐射对雄性小鼠的作用机制，以及确定所观察到现象的生物学意义。
