Shibata Naohiro, Kurokawa Hiroshi, Doi Yohei, Yagi Tetsuya, Yamane Kunikazu, Wachino Jun-ichi, Suzuki Satowa, Kimura Kouji, Ishikawa Satoshi, Kato Haru, Ozawa Yoshiyuki, Shibayama Keigo, Kai Kumiko, Konda Toshifumi, Arakawa Yoshichika
Department of Bacterial Pathogenesis and Infection Control, National Institute of Infectious Diseases, Tokyo, Japan.
Antimicrob Agents Chemother. 2006 Feb;50(2):791-5. doi: 10.1128/AAC.50.2.791-795.2006.
Of 1,456 strains isolated from 2001 to 2003 demonstrating resistance to either oxyimino-cephalosporin, 317 strains, isolated in 57 of 132 clinical facilities, were found to harbor bla(CTX-M) genes by PCR. Fifty-seven, 161, and 99 strains harbored bla(CTX-M) genes belonging to the bla(CTX-M-1), bla(CTX-M-2), and bla(CTX-M-9) clusters, respectively.
在2001年至2003年分离出的1456株对氧亚氨基头孢菌素耐药的菌株中,通过聚合酶链反应(PCR)发现,在132个临床机构中的57个机构分离出的317株菌株携带bla(CTX-M)基因。分别有57株、161株和99株菌株携带属于bla(CTX-M-1)、bla(CTX-M-2)和bla(CTX-M-9)簇的bla(CTX-M)基因。