Hung Chien-Jung, Huang Po-Chao, Li Yi-Hwei, Lu Shao-Chun, Ho Low-Tone, Chou Hsu-Fang
Department of Biochemistry, College of Medicine, Tzu-Chi University, Taiwan.
Br J Nutr. 2006 Jan;95(1):129-35. doi: 10.1079/bjn20051588.
The present study was designed to examine the effects of habitual consumption of Taiwanese vegetarian diets on hormonal secretion, and on lipid and glycaemic control. Of the ninety-eight healthy female adults recruited from Hualien, Taiwan (aged 31-45 years), forty-nine were Buddhist lactovegetarians and forty-nine were omnivores. Dietary intakes were measured, and blood levels of nutrients and hormones were analysed. Vegetarians consumed less energy, fat and protein, but more fibre than the omnivores. Compared with the omnivores, the vegetarians had, on average, lower BMI and smaller waist circumference. Except for slightly lower levels of thyroxine (T4) in vegetarians, vegetarians and omnivores both showed similar levels of triiodothyronine (T3), free T4, thyroid-stimulating hormone, T3:T4 ratio and cortisol. Compared with the omnivores, the vegetarians had significantly lower levels of fasting insulin (median: 35.3 v. 50.6 pmol/l) and plasma glucose (mean: 4.7 (se 0.05) v. 4.9 (se 0.05) mmol/l). Insulin resistance, as calculated by the homeostasis model assessment method, was significantly lower in the vegetarians than in the omnivores (median: 1.10 v. 1.56), while beta-cell function was not different between the two groups. BMI and diet were both independent predictors for insulin resistance, and contributed 18 and 15 % of the variation in insulin resistance, respectively. In conclusion, Taiwanese vegetarians had lower glucose and insulin levels and higher insulin sensitivity than did the omnivores. Diet and lower BMI were partially responsible for the high insulin sensitivity observed in young Taiwanese vegetarians.
本研究旨在探讨长期食用台湾素食对激素分泌以及脂质和血糖控制的影响。从台湾花莲招募了98名健康成年女性（年龄在31 - 45岁之间），其中49名是佛教乳素食者，49名是杂食者。测量了她们的饮食摄入量，并分析了血液中的营养物质和激素水平。素食者摄入的能量、脂肪和蛋白质比杂食者少，但纤维更多。与杂食者相比，素食者的平均体重指数（BMI）较低，腰围较小。除了素食者的甲状腺素（T4）水平略低外，素食者和杂食者的三碘甲状腺原氨酸（T3）、游离T4、促甲状腺激素、T3:T4比值和皮质醇水平相似。与杂食者相比，素食者的空腹胰岛素水平（中位数：35.3对50.6 pmol/l）和血糖水平（平均值：4.7（标准误0.05）对4.9（标准误0.05）mmol/l）显著较低。通过稳态模型评估法计算得出，素食者的胰岛素抵抗明显低于杂食者（中位数：1.10对1.56），而两组之间的β细胞功能没有差异。BMI和饮食都是胰岛素抵抗的独立预测因素，分别解释了胰岛素抵抗变异的18%和15%。总之，台湾素食者的血糖和胰岛素水平较低，胰岛素敏感性高于杂食者。饮食和较低的BMI部分解释了年轻台湾素食者中观察到的高胰岛素敏感性。
