Lee Yujin, Park Kyong
Department of Food and Nutrition, Yeungnam University, Gyeongsan 38541, Gyeongbuk, Korea.
Nutrients. 2017 Jun 14;9(6):603. doi: 10.3390/nu9060603.
We quantitatively assessed the association between a vegetarian diet and diabetes risk using pooled estimates from observational studies. Electronic database searches for articles published from January 1980 to May 2016 were independently performed by two investigators, and 13 articles (14 studies) were identified. The pooled odds ratio (OR) for diabetes in vegetarians vs. non-vegetarians was 0.726 (95% confidence interval (CI): 0.608, 0.867). In the subgroup analyses, this inverse association was stronger for the studies conducted in the Western Pacific region (OR 0.514, 95% CI: 0.304, 0.871) and Europe/North America (OR 0.756, 95% CI: 0.589, 0.971) than studies conducted in Southeast Asia (OR 0.888, 95% CI: 0.718, 1.099). No study had a substantial effect on the pooled effect size in the influence analysis, and the Egger's ( = 0.465) and Begg's tests ( = 0.584) revealed no publication bias. This meta-analysis indicates that a vegetarian diet is inversely associated with diabetes risk. Our results support the need for further investigations into the effects of the motivations for vegetarianism, the duration of the adherence to a vegetarian diet, and type of vegetarian on diabetes risk.
我们使用观察性研究的汇总估计值，对素食饮食与糖尿病风险之间的关联进行了定量评估。两名研究人员独立进行了电子数据库搜索，以查找1980年1月至2016年5月发表的文章，共确定了13篇文章（14项研究）。素食者与非素食者患糖尿病的合并优势比（OR）为0.726（95%置信区间（CI）：0.608, 0.867）。在亚组分析中，西太平洋地区（OR 0.514，95% CI：0.304, 0.871）和欧洲/北美（OR 0.756，95% CI：0.589, 0.971）开展的研究中，这种负相关关联比东南亚开展的研究（OR 0.888，95% CI：0.718, 1.099）更强。在影响分析中，没有研究对合并效应量有实质性影响，Egger检验（ = 0.465）和Begg检验（ = 0.584）显示无发表偏倚。这项荟萃分析表明，素食饮食与糖尿病风险呈负相关。我们的结果支持有必要进一步研究素食主义的动机、坚持素食饮食的持续时间以及素食类型对糖尿病风险的影响。
