Brown K E, Cohen B J
Virus Reference Laboratory, Central Public Health Laboratory, London, U.K.
J Gen Virol. 1992 Aug;73 ( Pt 8):2147-9. doi: 10.1099/0022-1317-73-8-2147.
Human parvovirus B19 is a member of the autonomous parvoviridae but in contrast to other members of the genus has not been shown to agglutinate red blood cells. We now report that the virus agglutinates red cells of primate origin, though with plasma-derived virus this activity is masked by the presence of an IgM-like inhibitor. This observation is consistent with the presence on the erythroid precursor target cell of a specific receptor for parvovirus B19.
人细小病毒B19是自主细小病毒科的成员，但与该属的其他成员不同，它未被证明能凝集红细胞。我们现在报告该病毒能凝集灵长类来源的红细胞，不过对于血浆来源的病毒，这种活性被一种IgM样抑制剂掩盖。这一观察结果与细小病毒B19在红系前体靶细胞上存在特异性受体相一致。
