Chaplin David D
University of Alabama at Birmingham, 845 19th Street South, Birmingham, AL 35294, USA.
J Allergy Clin Immunol. 2006 Feb;117(2 Suppl Mini-Primer):S430-5. doi: 10.1016/j.jaci.2005.09.034.
The human immune system mobilizes a broad repertoire of innate and adaptive responses to protect against the universe of pathogens it encounters. Central to these protective responses are its mechanisms to distinguish self from nonself. This overview describes the major mechanisms used by the immune system to respond to invading microbes and identifies settings in which disturbed immune function exacerbates tissue injury.
人类免疫系统会调动一系列广泛的先天性和适应性反应，以抵御其所遇到的各种病原体。这些保护性反应的核心是其区分自我与非自我的机制。本概述描述了免疫系统用于应对入侵微生物的主要机制，并确定了免疫功能紊乱会加剧组织损伤的情况。
