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预测经皮冠状动脉介入治疗院内死亡率的风险评分

A risk score to predict in-hospital mortality for percutaneous coronary interventions.

作者信息

Wu Chuntao, Hannan Edward L, Walford Gary, Ambrose John A, Holmes David R, King Spencer B, Clark Luther T, Katz Stanley, Sharma Samin, Jones Robert H

机构信息

University at Albany, State University of New York, Albany, New York, USA.

出版信息

J Am Coll Cardiol. 2006 Feb 7;47(3):654-60. doi: 10.1016/j.jacc.2005.09.071. Epub 2006 Jan 4.

Abstract

OBJECTIVES

Our purpose was to develop a risk score to predict in-hospital mortality for percutaneous coronary intervention (PCI) using a statewide population-based PCI registry.

BACKGROUND

Risk scores predicting adverse outcomes after PCI have been developed from a single or a small group of hospitals, and their abilities to be generalized to other patient populations might be affected.

METHODS

A logistic regression model was developed to predict in-hospital mortality for PCI using data from 46,090 procedures performed in 41 hospitals in the New York State Percutaneous Coronary Intervention Reporting System in 2002. A risk score was derived from this model and was validated using 2003 data from New York.

RESULTS

The risk score included nine significant risk factors (age, gender, hemodynamic state, ejection fraction, pre-procedural myocardial infarction, peripheral arterial disease, congestive heart disease, renal failure, and left main disease) that were consistent with other reports. The point values for risk factors range from 1 to 9, and the total risk score ranges from 0 to 40. The observed and recalibrated predicted risks in 2003 were highly correlated for all PCI patients as well as for those in the higher-risk subgroup who suffered myocardial infarctions within 24 h before the procedure. The total risk score for mortality is strongly associated with complication rates and length of stay in the 2003 PCI data.

CONCLUSIONS

The risk score accurately predicted in-hospital death for PCI procedures using future New York data. Its performance in other patient populations needs to be further studied.

摘要

目的

我们的目的是利用一个基于全州人口的经皮冠状动脉介入治疗(PCI)登记系统开发一个风险评分,以预测PCI患者的院内死亡率。

背景

预测PCI术后不良结局的风险评分是根据单一医院或一小群医院的数据开发的,其推广到其他患者群体的能力可能会受到影响。

方法

利用2002年纽约州经皮冠状动脉介入治疗报告系统中41家医院46090例手术的数据,建立逻辑回归模型来预测PCI患者的院内死亡率。从该模型中得出一个风险评分,并使用纽约2003年的数据进行验证。

结果

该风险评分包括九个显著的风险因素(年龄、性别、血流动力学状态、射血分数、术前心肌梗死、外周动脉疾病、充血性心脏病、肾衰竭和左主干病变),这些因素与其他报告一致。风险因素的分值范围为1至9,总风险评分范围为0至40。2003年,所有PCI患者以及术前24小时内发生心肌梗死的高风险亚组患者的观察到的和重新校准后的预测风险高度相关。在2003年的PCI数据中,死亡的总风险评分与并发症发生率和住院时间密切相关。

结论

该风险评分利用纽约未来的数据准确预测了PCI手术患者的院内死亡情况。其在其他患者群体中的表现需要进一步研究。

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