Delvaux Michel
Department of Internal Medicine and Digestive Pathology, Hôpitaux de Brabois Adultes, Tour Drouet, CHU de Nancy, F-54511 Vandoeuvre-les-Nancy, France.
Best Pract Res Clin Gastroenterol. 2006 Feb;20(1):23-39. doi: 10.1016/j.bpg.2005.08.002.
Capsule endoscopy has recently been introduced to explore endoscopically the whole small intestine, fulfilling a gap between examinations of the upper and lower gastrointestinal tract. The technique consists of a miniaturized endoscope, embedded in a swallowable capsule that is propulsed by peristalsis and achieves the journey to the right colon in five to eight hours. Images captured by the capsule are recorded on a hard drive worn in a belt by the patient. The main indication for capsule examination is the examination of the small bowel to find a bleeding lesion in patients with obscure bleeding. Several studies have shown that the diagnostic yield of capsule endoscopy is superior to that of push enteroscopy in this indication. Other possible indications are patients with suspected intestinal location of Crohn's disease, familial adenomatous polyposis, complicated coeliac disease and lesions due NSAIDs. The review contains information on the technical aspects of capsule endoscopy and discusses the indications. Issues of safety and tolerance are also discussed.
胶囊内镜最近被用于内镜检查整个小肠，填补了上消化道和下消化道检查之间的空白。该技术由一个小型化的内镜组成，它被嵌入一个可吞咽的胶囊中，通过蠕动推进，在五到八小时内到达右半结肠。胶囊捕获的图像记录在患者佩戴在腰带上的硬盘中。胶囊检查的主要适应证是检查小肠以发现不明原因出血患者的出血病变。几项研究表明，在该适应证方面，胶囊内镜的诊断率优于推进式小肠镜检查。其他可能的适应证包括疑似克罗恩病肠道定位、家族性腺瘤性息肉病、复杂性乳糜泻以及非甾体抗炎药所致病变的患者。这篇综述包含了胶囊内镜技术方面的信息并讨论了适应证。还讨论了安全性和耐受性问题。
