基层医疗患者广泛性焦虑症完全和部分康复的特征及预测因素
Characteristics and predictors of full and partial recovery from generalized anxiety disorder in primary care patients.
作者信息
Rodriguez Benjamin F, Weisberg Risa B, Pagano Maria E, Bruce Steven E, Spencer Michael A, Culpepper Larry, Keller Martin B
机构信息
Department of Psychology, Southern Illinois University at Carbondale, Carbondale, IL 62901-6502, USA.
出版信息
J Nerv Ment Dis. 2006 Feb;194(2):91-7. doi: 10.1097/01.nmd.0000198140.02154.32.
The current study examined the naturalistic course of generalized anxiety disorder (GAD) in a sample of 113 primary care patients across a 2-year period. Initial diagnoses were established using structured clinical interviews according to DSM-IV diagnostic criteria. Results indicated that the majority of patients meeting DSM-IV diagnostic criteria for GAD were still symptomatic to some degree after 2 years of follow-up. Rates of full and partial recovery from GAD, however, were found to be higher than those reported for previous studies of GAD in psychiatric patients. Diagnostic comorbidity, severity of psychosocial impairment, and gender were found to be significantly associated with achieving full or partial recovery from GAD. Psychiatric treatment was not found to be associated with time to full or partial recovery from GAD symptoms, likely due to a treatment-biasing effect. These results underscore that GAD is a chronic and persistent illness in primary care patients.
本研究在113名初级保健患者样本中，对广泛性焦虑障碍（GAD）的自然病程进行了为期两年的考察。根据DSM-IV诊断标准，通过结构化临床访谈确定初始诊断。结果表明，在两年的随访后，大多数符合DSM-IV广泛性焦虑障碍诊断标准的患者仍有一定程度的症状。然而，发现广泛性焦虑障碍完全康复和部分康复的比例高于先前针对精神病患者的广泛性焦虑障碍研究报告的比例。诊断合并症、心理社会损害的严重程度和性别被发现与广泛性焦虑障碍的完全或部分康复显著相关。未发现精神科治疗与广泛性焦虑障碍症状完全或部分康复的时间相关，这可能是由于治疗偏倚效应。这些结果强调，在初级保健患者中，广泛性焦虑障碍是一种慢性持续性疾病。
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