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妊娠期弓形虫病。

Toxoplasmosis during pregnancy.

作者信息

Many Ariel, Koren Gideon

机构信息

Motherrisk Program, Hospital for Sick Children, Toronto, Ontario.

出版信息

Can Fam Physician. 2006 Jan;52(1):29-30, 32.

PMID:16477906
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1479740/
Abstract

QUESTION

One of my female patients was tested for Toxoplasma and found positive for immunoglobulin G (IgG). She is planning to get pregnant soon. What are the risks for her and her baby?

ANSWER

Up to 25% of Canadians are IgG-positive for Toxoplasma due to past exposure. Immunoglobulin M (IgM) titres indicate current infection. Toxoplasma gondii is an obligate intracellular protozoan that has several forms during its life cycle: oocyte, tachyzoite, and cyst.

摘要

问题

我的一位女性患者接受了弓形虫检测，结果免疫球蛋白G（IgG）呈阳性。她计划不久后怀孕。这对她和她的宝宝有哪些风险？

答案

由于过去曾接触过，多达25%的加拿大人弓形虫IgG呈阳性。免疫球蛋白M（IgM）滴度表明当前感染情况。刚地弓形虫是一种专性细胞内原生动物，在其生命周期中有几种形态：卵母细胞、速殖子和包囊。

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Toxoplasmosis during pregnancy.妊娠期弓形虫病。
Can Fam Physician. 2006 Jan;52(1):29-30, 32.
2
Congenital toxoplasmosis and prenatal care state programs.先天性弓形虫病与产前保健州立项目。
BMC Infect Dis. 2014 Jan 18;14:33. doi: 10.1186/1471-2334-14-33.
3
Toxoplasmosis and pregnancy.弓形虫病与妊娠
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4
Toxoplasmosis in pregnancy is still an open subject.妊娠期弓形虫病仍然是一个未解决的课题。
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[The prevalence of Toxoplasma gondii infection among 2016 pregnant women and their children in the Institute of Mother and Child in Warsaw].[华沙母婴研究所2016名孕妇及其子女中弓形虫感染的患病率]
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[Spiramycin (Rovamycin) in the treatment of toxoplasmosis in pregnancy].
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Diagnosis of acute toxoplasmosis by IgG avidity method in pregnant women referred to health centers in south-eastern Iran.伊朗东南部转诊至健康中心的孕妇采用IgG亲和力法诊断急性弓形虫病。
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Preventing congenital toxoplasmosis.预防先天性弓形虫病。
MMWR Recomm Rep. 2000 Mar 31;49(RR-2):59-68.
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Seroprevalence of Toxoplasma gondii infection among veterinary staff in Ontario, Canada (2002): implications for teratogenic risk.加拿大安大略省兽医工作人员弓形虫感染血清流行率（2002年）：对致畸风险的影响
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Effect of timing and type of treatment on the risk of mother to child transmission of Toxoplasma gondii.治疗时机和类型对弓形虫母婴传播风险的影响。
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Toxoplasma gondii infection in the United States: seroprevalence and risk factors.美国的弓形虫感染：血清阳性率及危险因素
Am J Epidemiol. 2001 Aug 15;154(4):357-65. doi: 10.1093/aje/154.4.357.
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Mother-to-child transmission of toxoplasmosis: risk estimates for clinical counselling.弓形虫病的母婴传播：临床咨询的风险评估
Lancet. 1999 May 29;353(9167):1829-33. doi: 10.1016/S0140-6736(98)08220-8.
7
Treatment of toxoplasmosis during pregnancy: a multicenter study of impact on fetal transmission and children's sequelae at age 1 year.孕期弓形虫病的治疗：一项关于对胎儿传播及1岁儿童后遗症影响的多中心研究。
Am J Obstet Gynecol. 1999 Feb;180(2 Pt 1):410-5. doi: 10.1016/s0002-9378(99)70224-3.
8
Evaluation of six commercial kits for detection of human immunoglobulin M antibodies to Toxoplasma gondii. The FDA Toxoplasmosis Ad Hoc Working Group.六种用于检测弓形虫人类免疫球蛋白M抗体的商业试剂盒评估。美国食品药品监督管理局弓形虫病特别工作组。
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Outbreak of toxoplasmosis associated with municipal drinking water. The BC Toxoplasma Investigation Team.与市政饮用水相关的弓形虫病暴发。不列颠哥伦比亚省弓形虫调查小组。
Lancet. 1997 Jul 19;350(9072):173-7. doi: 10.1016/s0140-6736(96)11105-3.
10
Prenatal diagnosis of congenital toxoplasmosis with a polymerase-chain-reaction test on amniotic fluid.采用聚合酶链反应检测羊水进行先天性弓形虫病的产前诊断。
N Engl J Med. 1994 Sep 15;331(11):695-9. doi: 10.1056/NEJM199409153311102.