Chen Gary C, Enayati Pedram, Tran Tam, Lee-Henderson Mary, Quan Clifford, Dulai Gareth, Arnott Ian, Sul James, Jutabha Rome
UCLA Center for Small Bowel Diseases, UCLA Medical Center, Los Angeles, CA 90095-1684, United States.
World J Gastroenterol. 2006 Feb 28;12(8):1249-54. doi: 10.3748/wjg.v12.i8.1249.
To determine the performance of novice readers (4th year medical students) for detecting capsule endoscopy findings.
Ten capsule endoscopy cases of small bowel lesions were administered to the readers. Gold standard findings were pre-defined by gastroenterologists. Ten gold standard "targets" were identified among the 10 cases. Readers were given a 30-min overview of Rapid Reader software and instructed to mark any potential areas of abnormalities. A software program was developed using SAS to analyze the thumbnailed findings.
The overall sensitivity for detecting the gold standard findings was 80%. As a group, at least 5 out of 10 readers detected each gold standard finding per recording. All the gold standard targets were identified when the readers' results were combined. Incidental finding/false positive rate ranged between 8.2-59.8 per reader.
A panel of medical students with minimal endoscopic experience can achieve high sensitivity in detecting lesions on capsule endoscopy. A group of novice readers can pre-screen recordings to thumbnail potential areas of small bowel lesions for further review. These thumbnails must be reviewed to determine the clinical relevance. Further studies are ongoing to assess other cohorts.
确定新手读者（四年级医学生）检测胶囊内镜检查结果的能力。
向读者提供10例小肠病变的胶囊内镜病例。胃肠病学家预先确定了金标准结果。在这10例病例中确定了10个金标准“目标”。向读者提供了30分钟的Rapid Reader软件概述，并指导他们标记任何潜在的异常区域。使用SAS开发了一个软件程序来分析缩略图结果。
检测金标准结果的总体敏感性为80%。作为一个群体，每10名读者中至少有5人在每次记录中检测到每个金标准结果。当读者的结果合并时，所有金标准目标都被识别出来。每个读者的偶然发现/假阳性率在8.2%-59.8%之间。
一组内镜经验极少的医学生在检测胶囊内镜病变方面可获得高敏感性。一组新手读者可以对记录进行预筛查，以生成小肠病变潜在区域的缩略图以供进一步审查。必须对这些缩略图进行审查以确定其临床相关性。正在进行进一步研究以评估其他队列。
