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一项针对抑郁症患者的10年队列研究中的身体活动、运动应对与抑郁

Physical activity, exercise coping, and depression in a 10-year cohort study of depressed patients.

作者信息

Harris Alex H S, Cronkite Ruth, Moos Rudolf

机构信息

Center for Health Care Evaluation, Department of Veterans Affairs Health Care System and Stanford University, Menlo Park, California 94025, USA.

出版信息

J Affect Disord. 2006 Jul;93(1-3):79-85. doi: 10.1016/j.jad.2006.02.013. Epub 2006 Mar 20.

Abstract

BACKGROUND

Epidemiological research examining the relationship between physical activity and depression has been conducted almost exclusively with community samples. We examined associations between physical activity, exercise coping, and depression in a sample of initially depressed patients, using four waves of data spanning 10 years.

METHODS

A cohort (n=424) of depressed adults completed measures of physical activity, exercise coping, depression, and other demographic and psychosocial constructs at baseline, 1-year, 4-years, and 10-years, with a 90% wave-to-wave retention rate. Multilevel modeling was used to analyze individual depression trajectories.

RESULTS

More physical activity was associated with less concurrent depression, even after controlling for gender, age, medical problems, and negative life events. Physical activity counteracted the effects of medical conditions and negative life events on depression. However, physical activity was not associated with subsequent depression. The findings for exercise coping were comparable.

LIMITATIONS

Measures of physical activity and exercise coping encompassed a limited set of activities and did not include information about duration or intensity.

CONCLUSION

Our results suggest that more physical activity is associated with reduced concurrent depression. In addition, it appears that physical activity may be especially helpful in the context of medical problems and major life stressors. Clinically, encouraging depressed patients to engage in physical activity is likely to have potential benefits with few obvious risks.

摘要

背景

几乎所有关于身体活动与抑郁症之间关系的流行病学研究都仅在社区样本中进行。我们使用了跨越10年的四波数据,研究了最初患有抑郁症的患者样本中身体活动、运动应对方式与抑郁症之间的关联。

方法

一组(n = 424)抑郁症成年人在基线、1年、4年和10年时完成了身体活动、运动应对方式、抑郁症以及其他人口统计学和心理社会指标的测量,各波次的保留率为90%。采用多水平模型分析个体抑郁症轨迹。

结果

即使在控制了性别、年龄、医疗问题和负面生活事件之后,更多的身体活动仍与较低的当前抑郁症水平相关。身体活动抵消了医疗状况和负面生活事件对抑郁症的影响。然而,身体活动与随后的抑郁症并无关联。运动应对方式的研究结果与之类似。

局限性

身体活动和运动应对方式的测量涵盖的活动种类有限,且未包括持续时间或强度的信息。

结论

我们的结果表明,更多的身体活动与降低当前抑郁症水平相关。此外,身体活动在存在医疗问题和重大生活压力源的情况下似乎尤其有帮助。在临床上,鼓励抑郁症患者进行身体活动可能具有潜在益处,且几乎没有明显风险。

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