混合淋巴细胞细胞培养中的干扰素产生。
Interferon production in mixed lymphocyte cell cultures.
机构信息
Department of Immunology and Medical Microbiology, University of Florida College of Medicine, Gainesville, Florida 32601.
出版信息
Infect Immun. 1971 Jan;3(1):164-6. doi: 10.1128/iai.3.1.164-166.1971.
Abstract
Mixed lymphocyte cultures from mice with marked differences in major and minor histocompatibility antigens were found to produce an inhibitor of viral replication with properties of interferon. Cultures produced maximal amounts of interferon at approximately 72 to 96 hr, a time when maximal stimulation of deoxyribonucleic acid synthesis also occurred.
摘要
从主要和次要组织相容性抗原差异明显的小鼠混合淋巴细胞培养物中发现，有一种具有干扰素性质的病毒复制抑制剂。培养物在大约 72 到 96 小时产生最多量的干扰素，此时脱氧核糖核酸合成的最大刺激也发生。
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Interferon inducers protect mice against plasmodium berghei malaria.干扰素诱导剂可保护小鼠免受伯氏疟原虫疟疾的侵害。
Science. 1968 Aug 23;161(3843):802-4. doi: 10.1126/science.161.3843.802.
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