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潜伏梅毒:免疫荧光和其他血清学试验中反应的免疫球蛋白。

Latent syphilis: immunoglobulins reactive in immunofluorescence and other serological tests.

机构信息

Venereal Disease Research Laboratory, Center for Disease Control, Atlanta, Georgia 30333.

出版信息

Infect Immun. 1971 Apr;3(4):559-61. doi: 10.1128/iai.3.4.559-561.1971.

DOI:10.1128/iai.3.4.559-561.1971
PMID:16558017
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC416196/
Abstract

Study of sera from 69 patients with untreated or inadequately treated latent syphilis revealed that immunoglobulin (Ig)G antibodies made up the bulk of the fluorescent treponemal antibody-absorption (FTA-ABS)-test reactivity found in the sera. IgM and IgA antibodies also contributed in some cases. Venereal Disease Research Laboratory slide-test reactivity was found in both 19 and 7S serum fractions, whereas Treponema pallidum immobilization-test reactivity was found mainly in the 7S fraction.

摘要

对 69 例未经治疗或治疗不充分的潜伏梅毒患者的血清进行研究发现,在血清中发现的荧光密螺旋体抗体吸收(FTA-ABS)试验反应性主要由免疫球蛋白(Ig)G 抗体组成。在某些情况下,IgM 和 IgA 抗体也有贡献。性病研究实验室玻片试验反应性在 19 血清和 7S 血清部分中均有发现,而密螺旋体苍白密螺旋体固定试验反应性主要在 7S 部分发现。

相似文献

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Latent syphilis: immunoglobulins reactive in immunofluorescence and other serological tests.潜伏梅毒:免疫荧光和其他血清学试验中反应的免疫球蛋白。
Infect Immun. 1971 Apr;3(4):559-61. doi: 10.1128/iai.3.4.559-561.1971.
2
The fluorescent treponemal antibody-absorption (FTA-ABS) test for syphilis.梅毒荧光密螺旋体抗体吸收(FTA-ABS)试验
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Evaluation of the fluorescent treponemal antibody absorption test for detection of antibodies (immunoglobulins G and M) to Treponema pallidum in serologic diagnosis of syphilis.荧光密螺旋体抗体吸收试验用于梅毒血清学诊断中检测抗梅毒螺旋体抗体(免疫球蛋白G和M)的评估。
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Clinical comparison of the Treponema pallidum CAPTIA syphilis-G enzyme immunoassay with the fluorescent treponemal antibody absorption immunoglobulin G assay for syphilis testing.梅毒螺旋体CAPTIA梅毒-G酶免疫测定法与荧光密螺旋体抗体吸收免疫球蛋白G测定法用于梅毒检测的临床比较。
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引用本文的文献

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Immunological responses in late syphilis.梅毒晚期的免疫反应。
Br J Vener Dis. 1980 Dec;56(6):372-6. doi: 10.1136/sti.56.6.372.
2
Double-conjugate enzyme-linked immunosorbent assay for immunoglobulins G and M against Treponema pallidum.针对梅毒螺旋体的免疫球蛋白G和M的双共轭酶联免疫吸附测定法。
J Clin Microbiol. 1984 Dec;20(6):1109-13. doi: 10.1128/jcm.20.6.1109-1113.1984.
3
Ig class and IgG subclass responses to Treponema pallidum in patients with syphilis.梅毒患者对梅毒螺旋体的免疫球蛋白类别及IgG亚类反应。
J Clin Immunol. 1988 Mar;8(2):128-39. doi: 10.1007/BF00917901.
4
Immunoglobulin specificity for the fluorescent treponemal antibody-absorption test conjugate.荧光密螺旋体抗体吸收试验结合物的免疫球蛋白特异性。
J Clin Microbiol. 1976 Oct;4(4):338-42. doi: 10.1128/jcm.4.4.338-342.1976.
5
IgM-FTA test in syphilis in adults. Its relation to clinical findings.成人梅毒的IgM-FTA试验。其与临床发现的关系。
Br J Vener Dis. 1976 Aug;52(4):219-23. doi: 10.1136/sti.52.4.219.
6
Microassay for immunoglobulin G antibodies to Treponema pallidum with radioiodinated protein A from staphylococcus aureus: immunoglobulin G response in experimental syphilis in rabbits.用金黄色葡萄球菌放射性碘化蛋白A进行梅毒螺旋体免疫球蛋白G抗体的微量测定:兔实验性梅毒中的免疫球蛋白G反应
Infect Immun. 1978 Jul;21(1):163-70. doi: 10.1128/iai.21.1.163-170.1978.

本文引用的文献

1
THE TUSKEGEE STUDY OF UNTREATED SYPHILIS; THE 30TH YEAR OF OBSERVATION.塔斯基吉未治疗梅毒研究;第30年观察
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Effect of 2-mercaptoethanol treatment on anticardiolipin reactivity in sera from syphilitics and false positive reactors.2-巯基乙醇处理对梅毒患者和假阳性反应者血清中抗心磷脂反应性的影响。
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Fluorescent treponemal antibody-absorption (FTA-ABS) test for syphilis.梅毒荧光密螺旋体抗体吸收(FTA-ABS)试验
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4
Early syphilis: immunoglobulins reactive in immunofluorescence and other serologic tests.早期梅毒:免疫荧光及其他血清学检测中反应性免疫球蛋白
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5
Treated late syphilis: immunoglobulin class of antibodies reactive with Treponema pallidum.晚期梅毒治疗:与梅毒螺旋体反应的抗体免疫球蛋白类别。
J Invest Dermatol. 1969 Oct;53(4):300-1. doi: 10.1038/jid.1969.151.
6
The fluorescent treponemal antibody-absorption (FTA-ABS) test. Development, use and present status.荧光密螺旋体抗体吸收(FTA-ABS)试验。发展、应用及现状。
Bull World Health Organ. 1968;39(6):873-81.