细胞培养与酶免疫测定法放大技术在诊断生殖器单纯疱疹感染中的比较
Comparison of cell culture with an amplified enzyme immunoassay for diagnosing genital herpes simplex infection.
作者信息
Kudesia G, Van Hegan A, Wake S, Van Hegan R J, Kinghorn G R
机构信息
Public Health Laboratory, Northern General Hospital, Sheffield.
出版信息
J Clin Pathol. 1991 Sep;44(9):778-80. doi: 10.1136/jcp.44.9.778.
An amplified enzyme immunoassay (EIA) for herpes simplex virus (Novo Nordisk) was compared with cell culture in 853 genital specimens from a genito-urinary medicine clinic. The sensitivity of the EIA was 86% and its specificity 99.6%. The sensitivity increased to 94% for lesion swabs but decreased to 68% for cervical swabs. Sensitivity for urethral and vulval swabs was 83% and 82%, respectively. It is concluded that the EIA is specific and quick and easy to perform. It will be suitable for testing for genital herpes simplex infections in laboratories without access to local cell culture facilities.
在一家泌尿生殖医学诊所的853份生殖器标本中，将一种用于检测单纯疱疹病毒的扩增酶免疫测定法（EIA，诺和诺德公司产品）与细胞培养法进行了比较。该酶免疫测定法的敏感性为86%，特异性为99.6%。对于病损拭子，敏感性增至94%，但对于宫颈拭子，敏感性降至68%。尿道拭子和外阴拭子的敏感性分别为83%和82%。结论是，该酶免疫测定法具有特异性，操作快速简便。它将适用于没有当地细胞培养设施的实验室检测生殖器单纯疱疹感染。
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