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酶放大免疫测定法:一种应用于临床标本中沙眼衣原体直接检测的新技术。

Enzyme amplified immunoassay: a novel technique applied to direct detection of Chlamydia trachomatis in clinical specimens.

作者信息

Pugh S F, Slack R C, Caul E O, Paul I D, Appleton P N, Gatley S

出版信息

J Clin Pathol. 1985 Oct;38(10):1139-41. doi: 10.1136/jcp.38.10.1139.

Abstract

Endocervical swabs from 212 women and urethral swabs from 100 men were tested by the routine methods for McCoy cell culture and simultaneously by a novel enzyme amplified immunoassay test to detect chlamydia antigen. Overall correlation of the amplified test with culture was 96.5%. The test proved to be a suitable screening procedure for genital chlamydial infection, particularly for large numbers of specimens or in cases in which culture was not available.

摘要

采用常规方法对212名女性的宫颈拭子和100名男性的尿道拭子进行 McCoy 细胞培养检测,并同时采用一种新型酶扩增免疫分析试验检测衣原体抗原。扩增试验与培养的总体相关性为96.5%。该试验被证明是一种适用于生殖器衣原体感染的筛查方法,特别是对于大量标本或无法进行培养的情况。

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引用本文的文献

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Testing for Chlamydia trachomatis.沙眼衣原体检测
Can Fam Physician. 1988 Feb;34:399-402.
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9
Non specific genital infections: their diagnosis and clinical relevance.
Ir J Med Sci. 1988 Oct;157(10):326-7. doi: 10.1007/BF02954344.
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Clinical laboratory applications of monoclonal antibodies.单克隆抗体的临床实验室应用。
Clin Microbiol Rev. 1988 Jul;1(3):313-29. doi: 10.1128/CMR.1.3.313.

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