Paknejad Mojgan, Emtiaz Shahram, Khoobyari Mohammad Mohsen, Gharb Mehrnoush Teimouri, Yazdi Mojtaba Tabatabaei
Department of Periodontics, Faculty of Dentistry, Tehran University of Medical Sciences, Tehran, Iran.
Implant Dent. 2006 Mar;15(1):62-9. doi: 10.1097/01.id.0000202416.23259.35.
The aim of this investigation was to determine the presence of aspartate aminotransferase (AST) and alkaline phosphatase (ALP) in crevicular fluid collected from implants with and without clinical and radiographic signs of peri-implantitis.
There were 17 implants with symptoms of peri-implantitis in 12 subjects, including 4 females and 8 males, compared to 17 implants in 13 subjects, including 5 females and 8 males, with healthy peri-implant tissues. Filter paper strips were used to collect peri-implant crevicular fluid for 30 seconds in the base of the crevice/pocket. SPSS statistical software (SPSS, Inc., Chicago, IL) was used to determine AST and ALP activity.
The results showed that there was a significant difference in the activity of AST and ALP between the 2 study groups (P < 0.0001). AST activity was significantly associated with the amount of bleeding on probing (P = 0.02), but no statistical correlation was found between ALP activity and increased amount of bleeding on probing (P = 0.05).
Within the limits of this study, our results may suggest that peri-implant crevicular fluid analysis could be further investigated in longitudinal studies as a suitable diagnostic strategy in the evaluation of dental implants.
本研究的目的是确定从有和没有种植体周围炎临床及影像学表现的种植体采集的龈沟液中天门冬氨酸氨基转移酶（AST）和碱性磷酸酶（ALP）的存在情况。
12名受试者中有17颗种植体出现种植体周围炎症状，其中包括4名女性和8名男性，与之相比，13名受试者中有17颗种植体周围组织健康，其中包括5名女性和8名男性。使用滤纸条在龈沟/袋底部收集种植体周围龈沟液30秒。使用SPSS统计软件（SPSS公司，伊利诺伊州芝加哥）测定AST和ALP活性。
结果显示，两个研究组之间AST和ALP的活性存在显著差异（P < 0.0001）。AST活性与探诊出血的量显著相关（P = 0.02），但未发现ALP活性与探诊出血增加量之间存在统计学相关性（P = 0.05）。
在本研究的范围内，我们的结果可能表明，在纵向研究中，种植体周围龈沟液分析作为评估牙种植体的一种合适的诊断策略值得进一步研究。
