Fitzgerald Mary P, Mulligan Molly, Parthasarathy Sairam
Division of Female Pelvic Medicine and Reconstructive Surgery, Loyola University Medical Center, Maywood, IL, USA.
Am J Obstet Gynecol. 2006 May;194(5):1399-403. doi: 10.1016/j.ajog.2006.01.048. Epub 2006 Mar 30.
The purpose of this study was to determine the relationship between nocturia and obstructive sleep apnea (OSA), and the effect of continuous positive airways pressure (CPAP) therapy on nocturic frequency.
This was a retrospective review of sleep studies including patients with and without evidence of OSA, before and during CPAP treatment (where relevant). Chi-squared tests compared nocturia prevalence according to sleep diagnosis, logistic regression determined predictors of nocturia, and regression analyses determined predictors of nocturic frequency.
In 196 eligible studies, predictors of nocturia included increasing age and diabetes mellitus; nocturia was equally likely to occur in patients with and without OSA. In patients with OSA and nocturia, nocturic frequency was related to age, diabetes, and severity of OSA (P < .001). Patients with OSA and nocturia who were treated with CPAP demonstrated a significant decrease in nocturic frequency (P < .001).
OSA severity predicts nocturic frequency. The role of testing in the triage of patients with nocturia remains to be determined.
本研究旨在确定夜尿症与阻塞性睡眠呼吸暂停（OSA）之间的关系，以及持续气道正压通气（CPAP）治疗对夜尿频率的影响。
这是一项对睡眠研究的回顾性分析，纳入了有和没有OSA证据的患者，以及（如适用）CPAP治疗前和治疗期间的数据。卡方检验比较了根据睡眠诊断得出的夜尿症患病率，逻辑回归分析确定夜尿症的预测因素，回归分析确定夜尿频率的预测因素。
在196项符合条件的研究中，夜尿症的预测因素包括年龄增长和糖尿病；有和没有OSA的患者发生夜尿症的可能性相同。在患有OSA和夜尿症的患者中，夜尿频率与年龄、糖尿病和OSA严重程度相关（P < .001）。接受CPAP治疗的OSA合并夜尿症患者的夜尿频率显著降低（P < .001）。
OSA严重程度可预测夜尿频率。检测在夜尿症患者分诊中的作用仍有待确定。
