Takeuchi H, Ueda M, Satoh M, Yoshida O
Department of Urology, Faculty of Medicine, Kyoto University, Japan.
Urol Res. 1991;19(5):305-8. doi: 10.1007/BF00299065.
After feeding various diets we studied the effects of dietary calcium, magnesium and phosphorus on the formation of struvite stones in rats with urinary tract infections, and also studied the effects of the administration of vitamin D3 and aluminium gel on stone formation. A low-magnesium diet decreased urinary magnesium and prevented stone formation, but a medium-calcium diet did not significantly decrease stone weight. A high-calcium diet decreased urinary phosphorus and inhibited stone formation. A high-calcium and high-phosphorus diet decreased urinary excretion of magnesium and inhibited stone formation. Although the administration of vitamin D3 did not inhibit stone formation, aluminium gel decreased the urinary level of phosphorus and prevented stone formation. A marked decrease in urinary magnesium and/or phosphorus may prevent struvite stone formation in rats with urinary tract infections.
在给大鼠喂食不同饮食后，我们研究了膳食钙、镁和磷对患有尿路感染的大鼠鸟粪石形成的影响，还研究了给予维生素D3和铝凝胶对结石形成的影响。低镁饮食可降低尿镁水平并预防结石形成，但中等钙饮食并未显著降低结石重量。高钙饮食可降低尿磷水平并抑制结石形成。高钙高磷饮食可降低尿镁排泄并抑制结石形成。虽然给予维生素D3并未抑制结石形成，但铝凝胶可降低尿磷水平并预防结石形成。尿镁和/或磷的显著降低可能预防患有尿路感染的大鼠形成鸟粪石。
