Institut für Biochemie I der Universität Regensburg, Universitätsstrasse 31, D-8400 Regensburg, Federal Republic of Germany.
Proc Natl Acad Sci U S A. 1983 Sep;80(18):5470-4. doi: 10.1073/pnas.80.18.5470.
The Halobacterial cell wall glycoprotein was recently shown to contain two types of sulfated saccharides: a repetitive saccharide and a nonrepetitive saccharide composed of glucuronic acid and glucose. A new type of N-glycosidic linkage is found in this latter type of saccharide: glucose is N-glycosidically linked to the polypeptide chain through the amido nitrogen of an asparagine residue, as shown by chemical analyses, proton magnetic resonance spectroscopy, and mass spectroscopy of an isolated asparaginyl saccharide. The only N-glycosidic linkage known so far is between the amido nitrogen of asparagine and N-acetylglucosamine.
最近的研究表明，盐杆菌细胞壁糖蛋白含有两种类型的磺酸化糖：重复糖和非重复糖，后者由葡萄糖醛酸和葡萄糖组成。在后一种糖中发现了一种新型的 N-糖苷键：通过化学分析、质子磁共振波谱和分离的天冬酰胺糖的质谱分析表明，葡萄糖通过天冬酰胺残基的酰胺氮与多肽链发生 N-糖苷键连接。迄今为止，已知的唯一 N-糖苷键是天冬酰胺的酰胺氮和 N-乙酰葡萄糖胺之间的键。
