Liu Xianchen, Buysse Daniel J
Department of Psychiatry, University of Pittsburgh School of Medicine and Western Psychiatric Institute and Clinic, Pittsburgh, Pennsylvania, USA.
Curr Opin Psychiatry. 2006 May;19(3):288-93. doi: 10.1097/01.yco.0000218600.40593.18.
Sleep undergoes substantial changes during adolescence and suicide risk begins to increase during this period as well. This review focuses on recent literature on the relationship between sleep and suicidal behavior and proposes directions for future research.
Adolescent sleep is characterized by widespread sleep restriction, irregular sleep schedules, daytime sleepiness, and elevated risk for sleep disturbances. More research on adolescent sleep and psychosocial impairment, psychiatric disorders, and suicidal behavior has been conducted. Suicidal psychiatric patients had more sleep disturbances including insomnia, hypersomnia, or nightmares than nonsuicidal patients. Shorter rapid eye movement latency and increased rapid eye movement activity have been noted to be a marker of suicidality in psychiatric patients. Epidemiological studies have demonstrated that insomnia, nightmares, and sleep insufficiency are associated with elevated risk for suicide. Although the link between insomnia and suicidal behavior appears to be mediated by depression, existing data suggest an independent predictive role of nightmares in future suicidal behavior.
Sleep loss or disturbances are likely to signal an increased risk of future suicidal action in adolescents. Large-scale prospective studies and neurobiological studies are needed for a better understanding of the complex relationship between sleep, psychopathology, and youth suicidal behavior.
睡眠在青春期会发生显著变化,自杀风险在这一时期也开始上升。本综述聚焦于近期关于睡眠与自杀行为之间关系的文献,并提出未来研究方向。
青少年睡眠的特点是普遍存在睡眠限制、睡眠时间表不规律、白天嗜睡以及睡眠障碍风险增加。针对青少年睡眠与心理社会损害、精神疾病及自杀行为开展了更多研究。与无自杀倾向的患者相比,有自杀倾向的精神科患者存在更多睡眠障碍,包括失眠、嗜睡或噩梦。快速眼动睡眠潜伏期缩短和快速眼动睡眠活动增加被认为是精神科患者自杀倾向的一个标志。流行病学研究表明,失眠、噩梦和睡眠不足与自杀风险升高有关。虽然失眠与自杀行为之间的联系似乎由抑郁介导,但现有数据表明噩梦在未来自杀行为中具有独立的预测作用。
睡眠不足或睡眠障碍可能预示着青少年未来自杀行为风险增加。需要开展大规模前瞻性研究和神经生物学研究,以更好地理解睡眠、精神病理学与青少年自杀行为之间的复杂关系。