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2
Low prevalence of human papillomavirus types 16 and 18 in cervical adenocarcinoma in situ, invasive adenocarcinoma, and glandular dysplasia by polymerase chain reaction.通过聚合酶链反应检测人乳头瘤病毒16型和18型在宫颈原位腺癌、浸润性腺癌及腺发育异常中的低流行率
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A rhesus monkey model for sexual transmission of a papillomavirus isolated from a squamous cell carcinoma.一种从鳞状细胞癌中分离出的乳头瘤病毒性传播的恒河猴模型。
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4
Human papillomavirus detection in adenocarcinoma of the anus.
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5
Polymerase chain reaction analysis of human papillomavirus in adenocarcinoma and adenosquamous carcinoma of the uterine cervix.
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Immunol Cell Biol. 1987 Feb;65 ( Pt 1):77-84. doi: 10.1038/icb.1987.9.
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[Detection of HPV DNA in the uterine cervical lesions by polymerase chain reaction and in situ hybridization].[应用聚合酶链反应和原位杂交技术检测子宫颈病变中的人乳头瘤病毒DNA]
Nihon Sanka Fujinka Gakkai Zasshi. 1991 May;43(5):541-8.
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Increased detection of HPV 16 virus in invasive, but not in early cervical cancers.在浸润性宫颈癌中，人乳头瘤病毒16型（HPV 16）的检测率升高，但在早期宫颈癌中未升高。
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Analysis by polymerase chain reaction of the physical state of human papillomavirus type 16 DNA in cervical preneoplastic and neoplastic lesions.通过聚合酶链反应分析16型人乳头瘤病毒DNA在宫颈肿瘤前病变和肿瘤病变中的物理状态。
J Gen Virol. 1992 Sep;73 ( Pt 9):2327-36. doi: 10.1099/0022-1317-73-9-2327.

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Detection of human papillomavirus DNA in urine. A review of the literature.检测尿液中的人乳头瘤病毒 DNA。文献回顾。
Eur J Clin Microbiol Infect Dis. 2012 May;31(5):627-40. doi: 10.1007/s10096-011-1358-z. Epub 2011 Aug 5.
2
Meta-analysis of human papillomavirus infection concordance.HPV 感染一致性的荟萃分析。
Cancer Epidemiol Biomarkers Prev. 2010 Nov;19(11):2916-31. doi: 10.1158/1055-9965.EPI-10-0576. Epub 2010 Sep 10.
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Human papillomavirus infection and risk determinants for squamous intraepithelial lesion and cervical cancer in Japan.日本的人乳头瘤病毒感染与鳞状上皮内病变及宫颈癌的风险决定因素
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4
Human papillomavirus DNA in urine samples compared with that in simultaneously collected urethra and cervix samples.尿样中的人乳头瘤病毒DNA与同时采集的尿道和宫颈样本中的人乳头瘤病毒DNA的比较。
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Genitourin Med. 1995 Aug;71(4):231-3. doi: 10.1136/sti.71.4.231.
7
Identification of antibodies against human papillomavirus type 16 E6 and E7 proteins in sera of patients with cervical neoplasias.检测宫颈肿瘤患者血清中抗人乳头瘤病毒16型E6和E7蛋白的抗体
Jpn J Cancer Res. 1992 Jul;83(7):705-13. doi: 10.1111/j.1349-7006.1992.tb01970.x.

本文引用的文献

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Characteristics of women with dysplasia or carcinoma in situ of the cervix uteri.子宫颈发育异常或原位癌女性的特征。
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2
Human papillomaviruses in women with a history of abnormal Papanicolaou smears and in their male partners.有巴氏涂片异常病史的女性及其男性伴侣中的人乳头瘤病毒
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Enzymatic amplification of beta-globin genomic sequences and restriction site analysis for diagnosis of sickle cell anemia.用于镰状细胞贫血诊断的β-珠蛋白基因组序列的酶促扩增及限制性酶切位点分析。
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Occurrence of human papillomavirus types 16 and 18 DNA in cervical carcinomas from Japan: age of patients and histological type of carcinomas.
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Papillomavirus screening of cervical lavages by polymerase chain reaction.
Lancet. 1988 Dec 10;2(8624):1368. doi: 10.1016/s0140-6736(88)90906-3.
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Increased risk of cervical neoplasia in consorts of men with penile condylomata acuminata.阴茎尖锐湿疣男性配偶患宫颈瘤变的风险增加。
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Detection of human papillomavirus deoxyribonucleic acid in exfoliated cervicovaginal cells as a predictor of cervical neoplasia in a high-risk population.
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Detection of human papilloma virus in paraffin-embedded tissue using the polymerase chain reaction.利用聚合酶链反应检测石蜡包埋组织中的人乳头瘤病毒。
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New human papillomavirus sequences in female genital tumors from Japanese patients.日本患者女性生殖器肿瘤中的新型人乳头瘤病毒序列。
Jpn J Cancer Res. 1987 Oct;78(10):1081-7.
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Human papillomavirus detection in urine samples from male patients by the polymerase chain reaction.
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通过聚合酶链反应检测宫颈癌患者性伴侣中的16型人乳头瘤病毒。

Detection of human papillomavirus type 16 in sexual partners of patients having cervical cancer by polymerase chain reaction.

作者信息

Nakazawa A, Inoue M, Fujita M, Tanizawa O, Hakura A

机构信息

Department of Obstetrics and Gynecology, Osaka University Medical School.

出版信息

Jpn J Cancer Res. 1991 Nov;82(11):1187-90. doi: 10.1111/j.1349-7006.1991.tb01777.x.

DOI:10.1111/j.1349-7006.1991.tb01777.x
PMID:1661281
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5918319/
Abstract

The polymerase chain reaction (PCR) was employed to detect human papillomavirus (HPV) 16 and 18 in cytological samples from the uterine cervix and in urine samples from the male consorts. HPV 16 was detected in 2 (25%) of 8 males whose wives were positive for HPV 16, while it was detected in only one (7%) of 14 consorts whose wives were negative for HPV 16 and 18. This is the first report of the detection of HPV 16 in urine. Viral detection in urine samples by the PCR method is a non-invasive, convenient and useful tool for large-scale epidemiologic studies and investigations of the mechanism of virus transmission.

摘要

采用聚合酶链反应（PCR）检测子宫颈细胞学样本及男性配偶尿液样本中的人乳头瘤病毒（HPV）16和18型。在妻子HPV 16呈阳性的8名男性中，有2名（25%）检测出HPV 16，而在妻子HPV 16和18均呈阴性的14名配偶中，仅1名（7%）检测出HPV 16。这是尿液中检测出HPV 16的首次报道。通过PCR方法检测尿液样本中的病毒是一种用于大规模流行病学研究及病毒传播机制调查的非侵入性、便捷且有用的工具。