Kaspareit J, Friderichs-Gromoll S, Buse E, Habermann G
Department of Pathology, Covance Laboratories, Kesselfeld 29, 48163 Münster, Germany.
Exp Toxicol Pathol. 2006 Jul;57(5-6):405-10. doi: 10.1016/j.etp.2006.02.013. Epub 2006 Apr 17.
Two hundred common marmosets (Callithrix jacchus) from control groups (100 males, 100 females) of toxicological studies were examined histopathologically to evaluate the spectrum of spontaneous lesions in this species. Frequent findings were extramedullary hematopoiesis affecting adrenal glands, liver, kidney and spleen, cystic Brunner's glands in the duodenum, acute or subacute inflammation in the large intestine and gall bladder, renal mineralization and pigmentation, hepatic Ito-cell vacuolation, microgranuloma and glycogen storage, pituitary cysts, C-cell hyperplasia and lymphocytic foci of the thyroid gland, luteal hyperplasia of the ovary and inflammatory cell foci in various organs.
对毒理学研究对照组中的200只普通狨猴（Callithrix jacchus）（100只雄性，100只雌性）进行了组织病理学检查，以评估该物种自发病变的范围。常见的发现包括影响肾上腺、肝脏、肾脏和脾脏的髓外造血，十二指肠的囊性布伦纳腺，大肠和胆囊的急性或亚急性炎症，肾脏矿化和色素沉着，肝脏伊托细胞空泡化、微肉芽肿和糖原储存，垂体囊肿，甲状腺C细胞增生和淋巴细胞灶，卵巢黄体增生以及各器官的炎症细胞灶。
