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本文引用的文献

1
LPXTG protein InlJ, a newly identified internalin involved in Listeria monocytogenes virulence.LPXTG蛋白InlJ，一种新发现的与单核细胞增生李斯特菌毒力相关的内化素。
Infect Immun. 2005 Oct;73(10):6912-22. doi: 10.1128/IAI.73.10.6912-6922.2005.
2
Identification of novel stage-specific genetic requirements through whole genome transcription profiling of Vibrio cholerae biofilm development.通过霍乱弧菌生物膜发育的全基因组转录谱分析鉴定新的阶段特异性遗传需求。
Mol Microbiol. 2005 Sep;57(6):1623-35. doi: 10.1111/j.1365-2958.2005.04797.x.
3
Short fimbriae of Porphyromonas gingivalis and their role in coadhesion with Streptococcus gordonii.牙龈卟啉单胞菌的短菌毛及其在与戈登链球菌共黏附中的作用
Infect Immun. 2005 Jul;73(7):3983-9. doi: 10.1128/IAI.73.7.3983-3989.2005.
4
Initial subgingival colonization of 'pristine' pockets.“原始”牙周袋的初始龈下定植。
J Dent Res. 2005 Apr;84(4):340-4. doi: 10.1177/154405910508400409.
5
Differential protein expression by Porphyromonas gingivalis in response to secreted epithelial cell components.牙龈卟啉单胞菌对分泌的上皮细胞成分的差异蛋白表达
Proteomics. 2005 Jan;5(1):198-211. doi: 10.1002/pmic.200400922.
6
Identification of Porphyromonas gingivalis genes specifically expressed in human gingival epithelial cells by using differential display reverse transcription-PCR.利用差异显示逆转录聚合酶链反应鉴定牙龈卟啉单胞菌在人牙龈上皮细胞中特异性表达的基因。
Infect Immun. 2004 Jul;72(7):3752-8. doi: 10.1128/IAI.72.7.3752-3758.2004.
7
Environmental signals and regulatory pathways that influence biofilm formation.影响生物膜形成的环境信号和调控途径。
Mol Microbiol. 2004 May;52(4):917-24. doi: 10.1111/j.1365-2958.2004.04036.x.
8
Control of rpoS transcription in Escherichia coli and Pseudomonas: why so different?大肠杆菌和假单胞菌中rpoS转录的调控：为何差异如此之大？
Mol Microbiol. 2003 Jul;49(1):1-9. doi: 10.1046/j.1365-2958.2003.03547.x.
9
Invasion of mammalian cells by Listeria monocytogenes: functional mimicry to subvert cellular functions.单核细胞增生李斯特菌对哺乳动物细胞的侵袭：通过功能模拟来颠覆细胞功能
Trends Cell Biol. 2003 Jan;13(1):23-31. doi: 10.1016/s0962-8924(02)00006-5.
10
Role of the Streptococcus gordonii SspB protein in the development of Porphyromonas gingivalis biofilms on streptococcal substrates.戈登氏链球菌SspB蛋白在牙龈卟啉单胞菌在链球菌底物上生物膜形成中的作用。
Microbiology (Reading). 2002 Jun;148(Pt 6):1627-1636. doi: 10.1099/00221287-148-6-1627.

牙龈卟啉单胞菌InlJ蛋白在同型和异型生物膜形成中的作用

Role of the Porphyromonas gingivalis InlJ protein in homotypic and heterotypic biofilm development.

作者信息

Capestany Cindy A, Kuboniwa Masae, Jung Il-Young, Park Yoonsuk, Tribble Gena D, Lamont Richard J

机构信息

Department of Oral Biology, College of Dentistry, University of Florida, Gainesville, FL 32610-0424, USA.

出版信息

Infect Immun. 2006 May;74(5):3002-5. doi: 10.1128/IAI.74.5.3002-3005.2006.

DOI:10.1128/IAI.74.5.3002-3005.2006
PMID:16622239
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1459709/
Abstract

The oral pathogen Porphyromonas gingivalis expresses a homolog of the internalin family protein InlJ. Inactivation of inlJ reduced monospecies biofilm formation by P. gingivalis. In contrast, heterotypic P. gingivalis-Streptococcus gordonii biofilm formation was enhanced in the InlJ-deficient mutant. The results indicate a nuanced role for InlJ in regulating biofilm accumulations of P. gingivalis.

摘要

口腔病原体牙龈卟啉单胞菌表达内化素家族蛋白InlJ的同源物。inlJ的失活减少了牙龈卟啉单胞菌的单菌种生物膜形成。相比之下，在InlJ缺陷型突变体中，牙龈卟啉单胞菌与戈登链球菌的异型生物膜形成增强。结果表明InlJ在调节牙龈卟啉单胞菌生物膜积聚中具有微妙的作用。