二歧域A和B：来自芒萁的两种新的高氧化酚类衍生物。

Dichotomains A and B: two new highly oxygenated phenolic derivatives from Dicranopteris dichotoma.

作者信息

Li Xiao-Li, Cheng Xiao, Yang Liu-Meng, Wang Rui-Rui, Zheng Yong-Tang, Xiao Wei-Lie, Zhao Yu, Xu Gang, Lu Yang, Chang Ying, Zheng Qi-Tai, Zhao Qin-Shi, Sun Han-Dong

机构信息

State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650204, Yunnan, PRC.

出版信息

Org Lett. 2006 Apr 27;8(9):1937-40. doi: 10.1021/ol060535i.

DOI:10.1021/ol060535i

PMID:16623589

Abstract

[structure: see text] Dichotomains A (1) and B (2), two new highly oxygenated phenolic derivatives that feature a spirodilactone moiety in their structures, were isolated from the fronds of Dicranopteris dichotoma. Their structures were elucidated on the basis of NMR and MS spectroscopic data, and the stereochemistry of 1 was finally determined by single-crystal X-ray diffraction. Compound 2 showed weak anti-HIV-1 activity.

摘要

[结构：见正文] 二歧双歧蕨（Dicranopteris dichotoma）的叶中分离出了二歧双歧蕨素A（1）和二歧双歧蕨素B（2）这两种新的高度氧化的酚类衍生物，它们的结构中含有螺二内酯部分。基于核磁共振（NMR）和质谱（MS）光谱数据阐明了它们的结构，1的立体化学最终通过单晶X射线衍射确定。化合物2显示出较弱的抗HIV-1活性。