Li Xiao-Li, Cheng Xiao, Yang Liu-Meng, Wang Rui-Rui, Zheng Yong-Tang, Xiao Wei-Lie, Zhao Yu, Xu Gang, Lu Yang, Chang Ying, Zheng Qi-Tai, Zhao Qin-Shi, Sun Han-Dong
State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650204, Yunnan, PRC.
Org Lett. 2006 Apr 27;8(9):1937-40. doi: 10.1021/ol060535i.
[structure: see text] Dichotomains A (1) and B (2), two new highly oxygenated phenolic derivatives that feature a spirodilactone moiety in their structures, were isolated from the fronds of Dicranopteris dichotoma. Their structures were elucidated on the basis of NMR and MS spectroscopic data, and the stereochemistry of 1 was finally determined by single-crystal X-ray diffraction. Compound 2 showed weak anti-HIV-1 activity.
[结构：见正文] 二歧双歧蕨（Dicranopteris dichotoma）的叶中分离出了二歧双歧蕨素A（1）和二歧双歧蕨素B（2）这两种新的高度氧化的酚类衍生物，它们的结构中含有螺二内酯部分。基于核磁共振（NMR）和质谱（MS）光谱数据阐明了它们的结构，1的立体化学最终通过单晶X射线衍射确定。化合物2显示出较弱的抗HIV-1活性。
