Suppr超能文献

经巩膜二极管激光光凝术治疗难治性和非难治性青光眼的长期疗效及视力情况

Long-term efficacy and visual acuity following transscleral diode laser photocoagulation in cases of refractory and non-refractory glaucoma.

作者信息

Ansari E, Gandhewar J

机构信息

Eye Department, Eye, Ear & Mouth Unit, Maidstone Hospital, Maidstone, Kent, UK.

出版信息

Eye (Lond). 2007 Jul;21(7):936-40. doi: 10.1038/sj.eye.6702345. Epub 2006 Apr 21.

Abstract

AIMS

Transscleral diode laser cyclophotocoagulation (TSCP) is widely accepted in the treatment of refractory glaucoma especially in eyes with poor vision. However, until recently, there has been a reluctance to extend its use to eyes with good visual acuity (VA). The aims of this study were to evaluate the long-term efficacy and safety of TSCP for a range of glaucoma conditions, with particular emphasis on post-treatment VA in seeing eyes.

METHODS

A retrospective analysis of case notes of 74 treated eyes was conducted over a period of 4-30 months (mean 12.5 months).

RESULTS

Mean (SD) intraocular pressure (IOP) was reduced by 43% from 40.3 (6.7) to 21.1 mmHg (5.4) at the final index visit. Of all patients, 58% had a reduction in glaucoma drops and all discontinued oral Acetazolamide; 9% experienced complications. Mean VA was preserved in the subgroups with good vision, although 3/23 (13%) patients with primary open-angle glaucoma (POAG) lost vision due to cataract and glaucoma progression. There were no cases of hypotony (IOP<or=5 mmHg) or phthisis and only one eye required re-treatment.

CONCLUSIONS

TSCP is highly effective and safe for various types of glaucoma, and its use can be extended to eyes with good vision.

摘要

目的

经巩膜二极管激光睫状体光凝术(TSCP)在难治性青光眼尤其是视力较差的眼中的治疗已被广泛接受。然而,直到最近,人们仍不愿将其应用扩展到视力良好(VA)的眼睛。本研究的目的是评估TSCP对一系列青光眼病症的长期疗效和安全性,特别强调治疗后有视力眼的视力。

方法

对74只接受治疗的眼睛的病历进行了为期4至30个月(平均12.5个月)的回顾性分析。

结果

在最后一次指标访视时,平均(标准差)眼压(IOP)从40.3(6.7)mmHg降至21.1 mmHg(5.4),降低了43%。所有患者中,58%的患者青光眼药物用量减少,所有患者均停用口服乙酰唑胺;9%的患者出现并发症。视力良好的亚组中平均视力得以保留,尽管23例原发性开角型青光眼(POAG)患者中有3例(13%)因白内障和青光眼进展而丧失视力。没有发生低眼压(IOP≤5 mmHg)或眼球痨的病例,只有一只眼睛需要再次治疗。

结论

TSCP对各种类型的青光眼都非常有效且安全,其应用可以扩展到视力良好的眼睛。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验