Ansari E, Gandhewar J
Eye Department, Eye, Ear & Mouth Unit, Maidstone Hospital, Maidstone, Kent, UK.
Eye (Lond). 2007 Jul;21(7):936-40. doi: 10.1038/sj.eye.6702345. Epub 2006 Apr 21.
Transscleral diode laser cyclophotocoagulation (TSCP) is widely accepted in the treatment of refractory glaucoma especially in eyes with poor vision. However, until recently, there has been a reluctance to extend its use to eyes with good visual acuity (VA). The aims of this study were to evaluate the long-term efficacy and safety of TSCP for a range of glaucoma conditions, with particular emphasis on post-treatment VA in seeing eyes.
A retrospective analysis of case notes of 74 treated eyes was conducted over a period of 4-30 months (mean 12.5 months).
Mean (SD) intraocular pressure (IOP) was reduced by 43% from 40.3 (6.7) to 21.1 mmHg (5.4) at the final index visit. Of all patients, 58% had a reduction in glaucoma drops and all discontinued oral Acetazolamide; 9% experienced complications. Mean VA was preserved in the subgroups with good vision, although 3/23 (13%) patients with primary open-angle glaucoma (POAG) lost vision due to cataract and glaucoma progression. There were no cases of hypotony (IOP<or=5 mmHg) or phthisis and only one eye required re-treatment.
TSCP is highly effective and safe for various types of glaucoma, and its use can be extended to eyes with good vision.
经巩膜二极管激光睫状体光凝术(TSCP)在难治性青光眼尤其是视力较差的眼中的治疗已被广泛接受。然而,直到最近,人们仍不愿将其应用扩展到视力良好(VA)的眼睛。本研究的目的是评估TSCP对一系列青光眼病症的长期疗效和安全性,特别强调治疗后有视力眼的视力。
对74只接受治疗的眼睛的病历进行了为期4至30个月(平均12.5个月)的回顾性分析。
在最后一次指标访视时,平均(标准差)眼压(IOP)从40.3(6.7)mmHg降至21.1 mmHg(5.4),降低了43%。所有患者中,58%的患者青光眼药物用量减少,所有患者均停用口服乙酰唑胺;9%的患者出现并发症。视力良好的亚组中平均视力得以保留,尽管23例原发性开角型青光眼(POAG)患者中有3例(13%)因白内障和青光眼进展而丧失视力。没有发生低眼压(IOP≤5 mmHg)或眼球痨的病例,只有一只眼睛需要再次治疗。
TSCP对各种类型的青光眼都非常有效且安全,其应用可以扩展到视力良好的眼睛。