Pae Chi-Un
Department of Psychiatry, The Catholic University of Korea College of Medicine, Seoul, South Korea.
Prog Neuropsychopharmacol Biol Psychiatry. 2006 Aug 30;30(6):1143-5. doi: 10.1016/j.pnpbp.2006.03.015. Epub 2006 Apr 24.
The antagonism of 5-HT3 receptor by mirtazapine results in an antiemetic effect, suggesting that mirtazapine could be considered a successful antiemetic agent in patients suffering from severe nausea and vomiting. There have been several reports of successful mirtazapine treatment for nausea or vomiting from secondary causes but cases of primary severe nausea and vomiting are still lacking, in particular, there are no reported cases in Asians. The authors report two cases with severe nausea and vomiting that were dramatically treated with mirtazapine in the Korean population.
