柳叶五味子中的三萜类化合物。

Nortriterpenoids from Schisandra lancifolia.

作者信息

Xiao Wei-Lie, Huang Sheng-Xiong, Zhang Li, Tian Ren-Rong, Wu Li, Li Xiao-Li, Pu Jian-Xin, Zheng Yong-Tang, Lu Yang, Li Rong-Tao, Zheng Qi-Tai, Sun Han-Dong

机构信息

State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650204, Yunnan, People's Republic of China.

出版信息

J Nat Prod. 2006 Apr;69(4):650-3. doi: 10.1021/np060047j.

DOI:10.1021/np060047j

PMID:16643044

Abstract

Six new nortriterpenoids, lancifodilactones I-N (1-6), as well as nine known ones, were isolated from the leaves and stems of Schisandra lancifolia. Their structures were elucidated on the basis of spectroscopic methods including 2D NMR analysis, and the structures of compounds 1 and 4 were further confirmed by single-crystal X-ray crystallography. In addition, all new compounds were tested for anti-HIV-1 activity.

摘要

从披针叶五味子的叶和茎中分离出6个新的三萜类化合物，披针叶五味子内酯I-N（1-6），以及9个已知化合物。基于包括二维核磁共振分析在内的光谱方法阐明了它们的结构，化合物1和4的结构通过单晶X射线晶体学进一步得到确证。此外，对所有新化合物进行了抗HIV-1活性测试。