Xiao Wei-Lie, Li Xiao-Li, Wang Rui-Rui, Yang Liu-Meng, Li Li-Mei, Huang Sheng-Xiong, Pu Jian-Xin, Zheng Yong-Tang, Li Rong-Tao, Sun Han-Dong
State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650204, Yunnan, People's Republic of China.
J Nat Prod. 2007 Jun;70(6):1056-9. doi: 10.1021/np0700927. Epub 2007 May 10.
Investigation of an organic extract of Schisandra rubriflora led to the isolation of three new highly oxygenated nortriterpenoids, named rubriflorins A-C (1-3), together with six related known compounds (4-9). Their structures were elucidated by spectroscopic evidence. Compounds 1-3 feature the opening of ring A compared with related known nortriterpenoids isolated from the genus Schisandra and showed anti-HIV-1 activities with EC50 values of 10.0, 16.2, and 81.3 microg/mL, respectively.
对红花五味子的有机提取物进行研究，从中分离出三种新的高度氧化的降三萜类化合物，命名为红花五味子素A - C（1 - 3），以及六种相关的已知化合物（4 - 9）。通过光谱数据阐明了它们的结构。与从五味子属中分离出的相关已知降三萜类化合物相比，化合物1 - 3具有A环开环的特征，并显示出抗HIV - 1活性，其EC50值分别为10.0、16.2和81.3μg/mL。
