Solak M, Aktürk G, Erciyes N, Ozen I, Colak M, Duman E
Department of Anesthesia, Faculty of Medicine, Karadeniz Technical University, Trabzon, Turkey.
Acta Anaesthesiol Scand. 1991 Oct;35(7):572-4. doi: 10.1111/j.1399-6576.1991.tb03350.x.
A comparison of plain prilocaine and bicarbonated prilocaine in intravenous regional anesthesia was studied in 30 patients undergoing upper extremity surgery. The patients were divided into two groups: one group was given anesthesia in the form of 1% prilocaine and the other group was given 1% prilocaine plus sodium bicarbonate. The onset of analgesia and anesthesia and recovery from analgesia and anesthesia were investigated in both groups. Bicarbonated prilocaine produced faster onset of analgesia when compared with plain prilocaine (P less than 0.01). The onset of anesthesia and recovery from analgesia and anesthesia were not statistically different between the two groups. Clinically, the intensity of anesthesia was better when bicarbonated prilocaine solution was used instead of plain prilocaine. We conclude that bicarbonated prilocaine is better than plain prilocaine during IVRA.
对30例接受上肢手术的患者进行了研究，比较了普通丙胺卡因和碳酸氢钠丙胺卡因在静脉区域麻醉中的效果。患者被分为两组：一组给予1%丙胺卡因进行麻醉，另一组给予1%丙胺卡因加碳酸氢钠。对两组患者的镇痛和麻醉起效时间以及镇痛和麻醉恢复情况进行了研究。与普通丙胺卡因相比，碳酸氢钠丙胺卡因的镇痛起效更快（P<0.01）。两组之间的麻醉起效时间以及镇痛和麻醉恢复情况在统计学上无差异。临床上，使用碳酸氢钠丙胺卡因溶液时麻醉强度优于普通丙胺卡因。我们得出结论，在静脉区域麻醉期间，碳酸氢钠丙胺卡因比普通丙胺卡因更好。
