款冬花浸剂对流感病毒和单纯疱疹病毒的抗病毒活性。

Antiviral activity of Flos verbasci infusion against influenza and Herpes simplex viruses.

作者信息

Zgórniak-Nowosielska I, Grzybek J, Manolova N, Serkedjieva J, Zawilińska B

机构信息

Department of Virology, Medical Academy, Kraków, Poland.

出版信息

Arch Immunol Ther Exp (Warsz). 1991;39(1-2):103-8.

PMID:1666504

Abstract

The lyophilized infusion from flowers of Verbascum thapsiforme Schrad. (FVI) showed antiviral activity in in vitro studies against Fowl plague virus, several influenza A strains, influenza B strain as well as Herpes simplex virus. Influenza viruses titer decreased by 1-3 log units, while of H. simplex virus by 2.3 log. FVI has shown virucidal activity on H. simplex virus at 300 micrograms/ml, but did not inactivate influenza viruses. Phytochemical investigations of FVI have shown the presence of flavonoids, iridoids, phenolic acids, saponins, amino acids and free sugars.

摘要

绵毛叶玄参（Verbascum thapsiforme Schrad.）花的冻干浸膏（FVI）在体外研究中对鸡瘟病毒、几种甲型流感病毒株、乙型流感病毒株以及单纯疱疹病毒显示出抗病毒活性。流感病毒滴度降低了1 - 3个对数单位，而单纯疱疹病毒滴度降低了2.3个对数。FVI在300微克/毫升时对单纯疱疹病毒显示出杀病毒活性，但未使流感病毒失活。对FVI的植物化学研究表明其含有黄酮类化合物、环烯醚萜类、酚酸、皂苷、氨基酸和游离糖。