Castilla J, Arregui L, Baleztena J, Barricarte A, Brugos A, Carpintero M, Cortés F, Chérrez C, Díez J, Fernández-Alonso M, Figuerido E, Franco T, Gil A, Guijarro J L, Iceta A, Lacalle M T, Martín C, Martínez Mazo M D, Morán J, Moreno M, Palau J, Pérez-Afonso F, Rodríguez Macías A, Ruiz I, Senosiain M A, Sota M, Virto T, Vizcay J M, Yoldi C, Zubicoa J
Instituto de Salud Pública, Pamplona.
An Sist Sanit Navar. 2006 Jan-Apr;29(1):97-106.
To quantify the incidence of flu in different groups of the population of Navarra in the 2004-2005 season, and to evaluate the effectiveness of anti-flu vaccination.
The analysis of influenza cases in the system of compulsory notificable diseases was complemented by the individualised notifications in the network of sentinel doctors that covers a population of 22,339 inhabitants. The coverage and effectiveness of the vaccine was studied.
Vaccine coverage in (3)65 year olds reached 62%. The incidence of influenza was 42.6 cases per 1,000 inhabitants. It reached a maximum in mid-January, exceeding 750 weekly cases per 100,000 inhabitants and 1,900 cases per 100,000 children. The highest rate of influenza was observed in under-15 year olds (49.4 cases per 1,000 inhabitants) and the lowest in non-institutionalised (3)65 year olds (2.6 per 1,000 inhabitants), although it was higher in geriatric residences (62.1 per 1,000; p<0.0001). Seventy-nine percent of the cases from 5 to 64 years resulted in absenteeism from school or work. The flu virus was identified in 42/65 (65%) nasopharyngeal smears, 90% being influenza virus A(H3). The incidence of influenza was 3.08% in the unvaccinated and 0.45% in the vaccinated (p<0.001). The global effectiveness of the anti-flu vaccine was 65%, and in (3)65 years old it was 73%.
Although its effectiveness is not total, the vaccine is the main measure for preventing influenza. The network of sentinel doctors provide useful information for the coordination of care and public health activities against flu.
为了量化2004 - 2005年季节纳瓦拉不同人群中流感的发病率，并评估抗流感疫苗接种的效果。
对法定传染病系统中的流感病例分析，通过覆盖22339名居民的哨点医生网络的个体化报告进行补充。研究了疫苗的覆盖率和效果。
65岁及以上人群的疫苗覆盖率达到62%。流感发病率为每1000名居民42.6例。1月中旬达到最高，每10万居民每周超过750例，每10万儿童中超过1900例。15岁以下人群流感发病率最高（每1000名居民49.4例），非机构化65岁及以上人群最低（每1000名居民2.6例），尽管老年护理机构中发病率更高（每1000名居民62.1例；p<0.0001）。5至64岁的病例中有79%导致缺课或旷工。42/65（65%）的鼻咽涂片检测出流感病毒，90%为甲型（H3）流感病毒。未接种疫苗者的流感发病率为3.08%，接种疫苗者为0.45%（p<0.001）。抗流感疫苗的总体有效率为65%，65岁及以上人群为73%。
尽管疫苗效果并非完全有效，但它是预防流感的主要措施。哨点医生网络为流感防治的医疗协调和公共卫生活动提供了有用信息。
