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茶提取物对轮状病毒和肠道病毒感染的抑制作用。

Inhibition of rotavirus and enterovirus infections by tea extracts.

作者信息

Mukoyama A, Ushijima H, Nishimura S, Koike H, Toda M, Hara Y, Shimamura T

机构信息

Department of Enteroviruses, National Institute of Health, Tokyo, Japan.

出版信息

Jpn J Med Sci Biol. 1991 Aug;44(4):181-6. doi: 10.7883/yoken1952.44.181.

Abstract

Epigallocatechin gallate from green tea and theaflavin digallate from black tea inhibited infections of cultured rhesus monkey kidney MA 104 cells with rotaviruses and enteroviruses. Their antiviral effects were maximally induced when directly added to virus, and their pre- and post-treatment of the cells produced much weak antiviral activity. Antiviral activity of the extracts therefore seems to be attributable to interference with virus adsorption.

摘要

绿茶中的表没食子儿茶素没食子酸酯和红茶中的茶黄素双没食子酸酯可抑制轮状病毒和肠道病毒对恒河猴肾MA 104培养细胞的感染。将它们直接添加到病毒中时,其抗病毒效果达到最大诱导程度,而对细胞进行预处理和后处理产生的抗病毒活性则弱得多。因此,提取物的抗病毒活性似乎归因于对病毒吸附的干扰。

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