由亚磺酰亚胺衍生的吡咯烷-2-膦酸酯进行多官能化吡咯烷的不对称合成。吡咯烷225C的合成。
Asymmetric synthesis of polyfunctionalized pyrrolidines from sulfinimine-derived pyrrolidine 2-phosphonates. Synthesis of pyrrolidine 225C.
作者信息
Davis Franklin A, Xu He, Wu Yongzhong, Zhang Junyi
机构信息
Department of Chemistry, Temple University, Philadelphia, Pennsylvania 19122, USA.
出版信息
Org Lett. 2006 May 25;8(11):2273-6. doi: 10.1021/ol060521c.
Abstract
[reaction: see text] The Horner-Wadsworth-Emmons reaction of aldehydes with sulfinimine-derived 3-oxo pyrrolidine phosphonates represents a new method for the asymmetric synthesis of ring-functionalized cis-2,5-disubstituted 3-oxo pyrrolidines.
摘要
[反应：见正文] 醛与亚磺酰亚胺衍生的3-氧代吡咯烷膦酸酯的霍纳-沃兹沃思-埃蒙斯反应代表了一种不对称合成环官能化顺式-2,5-二取代3-氧代吡咯烷的新方法。
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