Vieira A, Lugtenborg M, Ruben J L, Huysmans M C D N J M
Department of Dentistry and Dental Hygiene, University of Groningen Medical Centre, Groningen, The Netherlands.
Caries Res. 2006;40(3):224-30. doi: 10.1159/000092230.
Topical fluorides have been proposed for the prevention of erosive dental wear. This study evaluated the in vitro effect of a single professional application of 4% titanium tetrafluoride (TiF4), 1% amine fluoride (AmF) and 0.1% difluorosilane varnish (FV) in preventing wear due to combined erosion and brushing abrasion. One hundred and eight bovine enamel samples were used. Control groups were not pretreated with any product (C), pretreated with a fluoride-free varnish (FV-bl) or pretreated with fluoride varnish and subsequently submitted to varnish removal (FV-r). Wear was modeled by submitting the fluoride-treated and control groups to 3 cycles of the following regimens: erosion/remineralization (er/remin), abrasion/remineralization (abr/remin) or erosion/abrasion/remineralization (er/abr/remin). Erosion was simulated by immersion of the samples for 10 min in citric acid 50 mM (pH 3). Abrasion was carried out for 1 min (200 strokes, load 150 g) in a wear device. Remineralization (2 h artificial saliva) took place between the cycles. Two-way ANOVA showed that there was a significant interaction (p<or=0.001) between the fluoride treatments and the wear regimens. Under er/remin a significant wear protective effect was found for the FV, FV-r and FV-bl groups. Abr/remin resulted in some enamel loss for the TiF4 and AmF groups, but the amounts lost were not statistically significant (p=0.185 and p=1.000, respectively). Under er/abr/remin all products showed a significant protective effect, except for TiF4. It was concluded that FV and AmF protected bovine enamel against erosion followed by brushing abrasion in vitro.
局部用氟化物已被提议用于预防牙侵蚀磨损。本研究评估了单次专业应用4%四氟化钛(TiF4)、1%氟化胺(AmF)和0.1%二氟硅烷清漆(FV)对预防因侵蚀和刷牙磨损共同作用导致的磨损的体外效果。使用了108个牛牙釉质样本。对照组未用任何产品预处理(C),用无氟清漆预处理(FV-bl)或用含氟清漆预处理,随后去除清漆(FV-r)。通过将经氟化物处理的组和对照组进行以下方案的3个循环来模拟磨损:侵蚀/再矿化(er/remin)、磨损/再矿化(abr/remin)或侵蚀/磨损/再矿化(er/abr/remin)。通过将样本在50 mM柠檬酸(pH 3)中浸泡10分钟来模拟侵蚀。在磨损装置中进行1分钟(200次冲程,负荷150克)的磨损。在各循环之间进行再矿化(2小时人工唾液)。双向方差分析表明,氟化物处理与磨损方案之间存在显著交互作用(p≤0.001)。在er/remin条件下,发现FV、FV-r和FV-bl组有显著的磨损保护作用。Abr/remin导致TiF4组和AmF组有一些牙釉质损失,但损失量无统计学意义(分别为p = 0.185和p = 1.000)。在er/abr/remin条件下,除TiF4外,所有产品均显示出显著的保护作用。得出的结论是,FV和AmF在体外可保护牛牙釉质免受侵蚀后再经刷牙磨损的影响。