Thorwarth M, Wehrhan F, Srour S, Schultze-Mosgau S, Felszeghy E, Bader R D, Schlegel K A
Department of Oral and Maxillofacial Surgery/Plastic Surgery, University of Jena, Erlanger Allee 101, D-07747 Jena, Germany.
Br J Oral Maxillofac Surg. 2007 Jan;45(1):41-7. doi: 10.1016/j.bjoms.2006.03.013. Epub 2006 May 19.
We created defects of standard size in the frontal bones of adult pigs and filled them with four different materials. On six occasions (at 1, 2, 4, 8, 12, and 26 weeks), samples were harvested, and evaluated by computing microradiographic images. We examined the specimens histologically as controls. After insertion of anorganic materials, microradiographic evaluation was easy and precise, and there were no significant differences between them and the histological controls (p=0.2). A quantitative evaluation of chemically sterilised bone by computer was not possible for more than 4 weeks.
我们在成年猪的额骨上制造了标准尺寸的缺损，并使用四种不同材料对其进行填充。在六个时间点（第1、2、4、8、12和26周）采集样本，并通过计算微放射图像进行评估。我们对标本进行组织学检查作为对照。植入无机材料后，微放射学评估简便且精确，且与组织学对照之间无显著差异（p = 0.2）。超过4周后无法通过计算机对化学消毒骨进行定量评估。
