Ishihara Takeshi, Yamaguchi Taketo, Seza Katsushi, Tadenuma Hiroshi, Saisho Hiromitsu
Department of Medicine and Clinical Oncology, Graduate School of Medicine, Chiba University, Chiba, Japan.
Scand J Gastroenterol. 2006 Jun;41(6):744-50. doi: 10.1080/00365520500383597.
Stents have been used to relieve pancreatic duct stricture and upstream dilatation. However, many of these stents are straight-type stents originally manufactured for biliary use. A plastic stent that was developed for use in the pancreatic duct was used in this study and its usefulness investigated.
The stent (s-type stent: 10 Fr in diameter) has two alternate flexions and the shape resembles the tilde mark " approximately " in appearance. After obtaining informed consent, stents were placed in 20 patients with abdominal pain caused by chronic pancreatitis and stricture of the distal main pancreatic duct. The stents were removed according to the clinical manifestations and replaced with new ones if the stricture persisted.
In total, 33 stents were placed in 20 patients. Pain relief was attained in 19 patients (95%). The stricture improved after one stenting in 8 patients (40%). Owing to persistent stricture, the stenting was repeated in 11 patients. The 50% stent indwelling period was 369.0 days. No proximal or distal migration of the stent occurred and there were no serious complications.
In view of its long durability as a stent and no migration, the s-stent is safe and useful for the management of pancreatic ductal strictures in patients with chronic pancreatitis.
支架已被用于缓解胰管狭窄和上游扩张。然而，这些支架中的许多是最初为胆道使用而制造的直管型支架。本研究使用了一种专为胰管使用而开发的塑料支架，并对其有效性进行了研究。
该支架（s型支架：直径10Fr）有两个交替的弯曲，外观形状类似于波浪号“～”。在获得知情同意后，将支架放置在20例因慢性胰腺炎和主胰管远端狭窄引起腹痛的患者中。根据临床表现取出支架，如果狭窄持续存在则更换新的支架。
20例患者共放置了33个支架。19例患者（95%）疼痛缓解。8例患者（40%）一次置入支架后狭窄得到改善。由于狭窄持续存在，11例患者重复进行了支架置入。支架的50%留置期为369.0天。未发生支架近端或远端移位，也没有严重并发症。
鉴于s型支架作为支架具有长期耐用性且无移位，对于慢性胰腺炎患者胰管狭窄的治疗是安全且有效的。
