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探究音乐对轻度阿尔茨海默病患者自传体记忆的增强作用。

Investigating the enhancing effect of music on autobiographical memory in mild Alzheimer's disease.

作者信息

Irish Muireann, Cunningham Conal J, Walsh J Bernard, Coakley Davis, Lawlor Brian A, Robertson Ian H, Coen Robert F

机构信息

Mercer's Institute for Research on Ageing, St. James's Hospital, Dublin, Ireland.

出版信息

Dement Geriatr Cogn Disord. 2006;22(1):108-20. doi: 10.1159/000093487. Epub 2006 May 23.

DOI:10.1159/000093487
PMID:16717466
Abstract

The enhancing effect of music on autobiographical memory recall in mild Alzheimer's disease individuals (n = 10; Mini-Mental State Examination score >17/30) and healthy elderly matched individuals (n = 10; Mini-Mental State Examination score 25-30) was investigated. Using a repeated-measures design, each participant was seen on two occasions: once in music condition (Vivaldi's 'Spring' movement from 'The Four Seasons') and once in silence condition, with order counterbalanced. Considerable improvement was found for Alzheimer individuals' recall on the Autobiographical Memory Interview in the music condition, with an interaction for condition by group (p < 0.005). There were no differences in terms of overall arousal using galvanic skin response recordings or attentional errors during the Sustained Attention to Response Task. A significant reduction in state anxiety was found on the State Trait Anxiety Inventory in the music condition (p < 0.001), suggesting anxiety reduction as a potential mechanism underlying the enhancing effect of music on autobiographical memory recall.

摘要

研究了音乐对轻度阿尔茨海默病患者(n = 10;简易精神状态检查表得分>17/30)和年龄匹配的健康老年人(n = 10;简易精神状态检查表得分25 - 30)自传体记忆回忆的增强作用。采用重复测量设计,每位参与者接受两次测试:一次处于音乐环境(维瓦尔第《四季》中的“春”乐章),一次处于安静环境,顺序随机平衡。研究发现,在音乐环境中,阿尔茨海默病患者在自传体记忆访谈中的回忆有显著改善,且存在环境与组别的交互作用(p < 0.005)。在使用皮肤电反应记录的总体唤醒水平或持续注意力反应任务中的注意力错误方面,两组没有差异。在音乐环境中,状态特质焦虑量表显示状态焦虑显著降低(p < 0.001),这表明焦虑减轻是音乐对自传体记忆回忆产生增强作用的潜在机制。

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