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基于瑞典市场篮子数据对有机卤素污染物(二噁英、多氯联苯、多溴二苯醚和氯化农药,如滴滴涕)的膳食摄入量估计。

Dietary intake estimations of organohalogen contaminants (dioxins, PCB, PBDE and chlorinated pesticides, e.g. DDT) based on Swedish market basket data.

作者信息

Darnerud P O, Atuma S, Aune M, Bjerselius R, Glynn A, Grawé K Petersson, Becker W

机构信息

Toxicology Division, National Food Administration, P.O. Box 622, SE-751 26 Uppsala, Sweden.

出版信息

Food Chem Toxicol. 2006 Sep;44(9):1597-606. doi: 10.1016/j.fct.2006.03.011. Epub 2006 Apr 6.

Abstract

By use of a Swedish Market basket study from 1999, in which foods were sampled from four regions, the dietary intake of persistent organic pollutants (POPs) was assessed. Based on earlier data, six food groups (fish, meat, dairy products, egg, fats/oils, and pastries; comprising 52 food items) were selected for POP analyses. Homogenates from these six groups were subjected to POP analyses and levels presented on dioxins (PCDD/PCDFs), dioxin-like PCBs, PCB-153, summation operatorPCBs, BDE-47, summation operatorPBDEs, DDE, summation operatorDDTs, HCB, summation operatorHCHs, and summation operatorchlordanes, after adjusting non-quantified levels to 1/2 LOQ. For all compounds, the fish homogenate contained the comparatively highest levels, on a fresh weight basis. Intake calculations based on the six food groups showed that summation operatorPCBs and summation operatorDDTs gave per capita intakes of 615 and 523 ng/day, respectively, that the estimated summation operatorPBDE intake was 51 ng/day and that of dioxins and dioxin-like PCBs was 96 pg WHO-TEQ/day. The estimated mean intakes were below (total-TEQ: 1.3 pg/kgbw/day) or well below (summation operatorDDTs: 8.9 ng/kgbw/day) internationally agreed intake limits (total-TEQ: 2 pg/kgbw/day; summation operatorDDTs: 10,000 ng/kgbw/day). A number of uncertainty factors, including analytical limitations due to low POP levels in food, give reason for caution in the use of the presented intake data. However, the intake estimations of dioxins, summation operatorPCBs and summation operatorPBDEs are well in accordance to calculations of POP intakes in Sweden made by alternate methods.

摘要

通过使用1999年瑞典市场篮子研究(该研究从四个地区采集食物样本),对持久性有机污染物(POPs)的膳食摄入量进行了评估。根据早期数据,选择了六个食物组(鱼、肉、乳制品、蛋、脂肪/油和糕点;包含52种食物)进行POP分析。对这六个组的匀浆进行POP分析,并在将未定量水平调整为1/2最低定量限后,给出二恶英(PCDD/PCDFs)、类二恶英多氯联苯、PCB - 153、总多氯联苯、BDE - 47、总多溴二苯醚、DDE、总滴滴涕、六氯苯、总六氯环己烷和总氯丹的含量水平。对于所有化合物,以鲜重计,鱼匀浆中的含量相对最高。基于这六个食物组的摄入量计算表明,总多氯联苯和总滴滴涕的人均摄入量分别为615和523纳克/天,估计总多溴二苯醚摄入量为51纳克/天,二恶英和类二恶英多氯联苯的摄入量为96皮克WHO - TEQ/天。估计的平均摄入量低于(总TEQ:1.3皮克/千克体重/天)或远低于(总滴滴涕:8.9纳克/千克体重/天)国际商定的摄入限值(总TEQ:2皮克/千克体重/天;总滴滴涕:10,000纳克/千克体重/天)。包括食物中POPs含量低导致的分析局限性在内的一些不确定因素,使得在使用所呈现的摄入数据时需谨慎。然而,二恶英、总多氯联苯和总多溴二苯醚的摄入量估计与瑞典采用其他方法计算的POP摄入量计算结果非常一致。

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