氟化物应用后各种牙科材料的氟释放与吸收

Fluoride release and uptake by various dental materials after fluoride application.

作者信息

Okuyama Katsushi, Murata Yasuhiro, Pereira Patricia N R, Miguez Patricia Almeida, Komatsu Hisanori, Sano Hidehiko

机构信息

Department of Restorative Dentistry, Division of Oral Health Science, Hokkaido University Graduate School of Dental Medicine, Sapporo, Japan.

出版信息

Am J Dent. 2006 Apr;19(2):123-7.

PMID:16764137

Abstract

PURPOSE

To measure the amounts of fluoride released from fluoride-containing materials before and after daily topical fluoride applications.

METHODS

A conventional glass-ionomer: Fuji Ionomer Type II (F2); a resin-modified glass-ionomer: Fuji Ionomer Type II LC (LC); two "giomer" materials: Reactmer Paste (RP), and Beautifil (BT); a fluoride-containing resin composite: Unifil F (UF); and a non-fluoride resin composite: AP-X (AP) were used in this study. Each material was filled into a plastic mold, with inner diameter of 9 mm wide x 3 mm high. The specimens were stored in vials filled with 8 ml distilled deionized water for 24 hours at 37 degrees C. The specimens were then removed from the vials and the amount of fluoride released into the water, over the 24-hour period, was measured. The amount of fluoride released was measured by using specific fluoride electrode and an ion-analyzer. These procedures were repeated at Days 2, 3, 7, 14, and 21. After 21 days, all specimens were exposed to 1000 ppm F NaF solution for 5 minutes once a day. This procedure and measurement of fluoride release were continued for 14 days. After 14 days, the specimens were placed in water for 7 days and fluoride release was measured. The results were statistically analyzed using Kruskal-Wallis and Mann-Whitney U-test (P< 0.05).

RESULTS

At the 22nd day (1 day after starting fluoride exposure), there was no difference between the F2 and RP, though there were significant differences between the two GICs and the groups BT and UF. After that day, there were significant differences between GIC and the group RP, BT and UF. All materials showed a decrease in fluoride release 7 days after end of the fluoride immersion period. F2, LC, and UF showed no significant difference of fluoride release between Day 21 and 1 day after the end of the fluoride immersion period (P= 0.310: F2 and UF, 0.548: LC). On the other hand, RP and BT revealed lower fluoride release 1 day after the end of the fluoride immersion period as compared to Day 21 (P= 0.075: RP, 1.000: BT). For AP, fluoride release was not detected after the fluoride immersion period.

摘要

目的

测量每日局部应用氟化物前后含氟材料释放的氟化物量。

方法

本研究使用了一种传统玻璃离子水门汀：富士II型玻璃离子水门汀（F2）；一种树脂改性玻璃离子水门汀：富士II型LC玻璃离子水门汀（LC）；两种“聚酸改性复合树脂”材料：Reactmer糊剂（RP）和Beautifil（BT）；一种含氟树脂复合材料：Unifil F（UF）；以及一种不含氟的树脂复合材料：AP-X（AP）。将每种材料填充到内径为9毫米宽×3毫米高的塑料模具中。将标本储存在装有8毫升蒸馏去离子水的小瓶中，在37摄氏度下放置24小时。然后将标本从小瓶中取出，测量24小时内释放到水中的氟化物量。使用特定的氟电极和离子分析仪测量释放的氟化物量。在第2、3、7、14和21天重复这些步骤。21天后，所有标本每天暴露于1000 ppm氟化钠溶液中5分钟，持续14天。继续进行该程序并测量氟化物释放量。14天后，将标本置于水中7天并测量氟化物释放量。使用Kruskal-Wallis和Mann-Whitney U检验对结果进行统计学分析（P<0.05）。

结果

在第22天（开始暴露于氟化物1天后），F2和RP之间没有差异，尽管两种玻璃离子水门汀与BT组和UF组之间存在显著差异。在那一天之后，玻璃离子水门汀与RP组、BT组和UF组之间存在显著差异。在氟化物浸泡期结束后7天，所有材料的氟化物释放量均有所下降。F2、LC和UF在第21天和氟化物浸泡期结束后1天之间的氟化物释放量没有显著差异（P = 0.310：F2和UF，0.548：LC）。另一方面，RP和BT在氟化物浸泡期结束后1天的氟化物释放量低于第21天（P = 0.075：RP，1.000：BT）。对于AP，在氟化物浸泡期后未检测到氟化物释放。