Nosaka Kazunori, Chapman Dale, Newton Mike, Sacco Paul
School of Exercise, Biomedical and Health Sciences, Edith Cowan University, Joondalup, Australia.
Appl Physiol Nutr Metab. 2006 Jun;31(3):313-9. doi: 10.1139/h06-005.
This study tested the hypothesis that the magnitude of maximal isometric strength (MVC) loss immediately following eccentric exercise (MVC-post) would relate to changes in other indirect markers of muscle damage following exercise. Eighty-nine men were recruited from the same student population and performed 24 maximal eccentric actions of the elbow flexors. Commonly used markers of muscle damage such as relaxed and flexed elbow joint angles, range of motion (ROM), upper-arm circumference, muscle soreness, and plasma creatine kinase (CK) activity were measured before, immediately after, and 1-4 d after exercise. Pearson's product-moment correlation coefficients (r) between change in MVC-post and other markers of muscle damage, as well as MVC during recovery days, were calculated. Changes in MVC-post ranged from -72.8% to -17.6%, and correlated significantly (p < 0.01) with MVC at 1 (r = 0.59), 2 (0.63), 3 (0.61), and 4 (0.62) d after exercise. Reduction in MVC-post also correlated significantly (p < 0.05) with changes in relaxed (r = 0.50) and flexed elbow joint angles (-0.40), ROM (0.55), arm circumference (-0.45), peak palpation (-0.34) and extension muscle soreness (-0.48), and peak CK activity (-0.59). However, the r values were not necessarily high, and MVC-post poorly reflected the distribution of some measures, such as peak CK activity (124 - 50 440 IU x L(-1). These results suggest that MVC-post is not a strong correlate of the changes in markers of muscle damage following eccentric exercise of the elbow flexors.
离心运动后即刻最大等长力量（MVC）的下降幅度（MVC-运动后）与运动后其他肌肉损伤间接标志物的变化相关。从同一学生群体中招募了89名男性，他们进行了24次肘关节屈肌的最大离心动作。在运动前、运动后即刻以及运动后1 - 4天，测量了常用的肌肉损伤标志物，如放松和屈曲时的肘关节角度、活动范围（ROM）、上臂围度、肌肉酸痛以及血浆肌酸激酶（CK）活性。计算了MVC-运动后变化与其他肌肉损伤标志物以及恢复期间MVC之间的Pearson积矩相关系数（r）。MVC-运动后的变化范围为-72.8%至-17.6%，并且与运动后第1天（r = 0.59）、第2天（0.63）、第3天（0.61）和第4天（0.62）的MVC显著相关（p < 0.01）。MVC-运动后的下降也与放松时肘关节角度的变化（r = 0.50）、屈曲时肘关节角度的变化（-0.40）、ROM（0.55）、上臂围度（-0.45）、触诊峰值（-0.34）和伸展肌酸痛（-0.48）以及CK活性峰值（-0.59）显著相关（p < 0.05）。然而，r值不一定很高，并且MVC-运动后不能很好地反映某些指标的分布情况，如CK活性峰值（124 - 50440 IU×L⁻¹）。这些结果表明，MVC-运动后与肘关节屈肌离心运动后肌肉损伤标志物的变化并非强相关。
