Haynes Laura, Swain Susan L
Trudeau Institute, Inc., Saranac Lake, New York 12983.
Trudeau Institute, Inc., Saranac Lake, New York 12983.
Immunity. 2006 Jun;24(6):663-666. doi: 10.1016/j.immuni.2006.06.003.
The decline in CD4+ T cell function with aging contributes to reduced vaccine efficacy. In this commentary, we discuss the factors leading to age-related changes in T cell function and propose how they may be overcome to enhance vaccine efficacy for the elderly.
随着年龄增长,CD4+ T细胞功能下降导致疫苗效力降低。在这篇评论中,我们讨论了导致T细胞功能出现与年龄相关变化的因素,并提出如何克服这些因素以提高老年人的疫苗效力。