衰老T细胞功能衰退的原因：对疫苗接种的影响。

Why aging T cells fail: implications for vaccination.

作者信息

Haynes Laura, Swain Susan L

机构信息

Trudeau Institute, Inc., Saranac Lake, New York 12983.

Trudeau Institute, Inc., Saranac Lake, New York 12983.

出版信息

Immunity. 2006 Jun;24(6):663-666. doi: 10.1016/j.immuni.2006.06.003.

DOI:10.1016/j.immuni.2006.06.003
PMID:16782020
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7129126/
Abstract

The decline in CD4+ T cell function with aging contributes to reduced vaccine efficacy. In this commentary, we discuss the factors leading to age-related changes in T cell function and propose how they may be overcome to enhance vaccine efficacy for the elderly.

摘要

随着年龄增长，CD4+ T细胞功能下降导致疫苗效力降低。在这篇评论中，我们讨论了导致T细胞功能出现与年龄相关变化的因素，并提出如何克服这些因素以提高老年人的疫苗效力。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4054/7129126/f893aa1064d2/gr1_lrg.jpg

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