Molloy E J, Deakins K
Division of Neonatology, National Maternity Hospital, Dublin, Ireland.
Arch Dis Child Fetal Neonatal Ed. 2006 Jul;91(4):F295-8. doi: 10.1136/adc.2005.082008.
Maintenance of neonatal normocarbia may prevent chronic lung disease and periventricular leucomalacia, but this requires frequent arterial sampling, which has risks. Alternative methods for measuring CO2 are therefore desirable. These include end tidal CO2, capillary sampling, and transcutaneous measurements. CO2 detectors have also proved effective and rapid indicators of endotracheal intubation. However, this method relies on the presence of exhaled CO2, which may be reduced in certain situations, such as cardiopulmonary arrest. Colorimetric CO2 detectors are therefore valuable adjuncts for airway management, especially during resuscitation, but Pa(CO2) is still the best measure of CO2 in neonatal practice.
维持新生儿正常碳酸血症可预防慢性肺病和脑室周围白质软化，但这需要频繁进行动脉采样，而动脉采样存在风险。因此，需要其他测量二氧化碳的方法。这些方法包括呼气末二氧化碳监测、毛细血管采样和经皮测量。二氧化碳探测器也已被证明是气管插管的有效且快速的指标。然而，这种方法依赖于呼出二氧化碳的存在，在某些情况下，如心肺骤停时，呼出二氧化碳可能会减少。因此，比色法二氧化碳探测器是气道管理的重要辅助手段，尤其是在复苏过程中，但在新生儿实践中，动脉血二氧化碳分压（Pa(CO2)）仍然是测量二氧化碳的最佳指标。
