轮状病毒G9血清型与拉丁美洲更严重的疾病有关。
Rotavirus serotype G9 is associated with more-severe disease in Latin America.
作者信息
Linhares A C, Verstraeten Thomas, Wolleswinkel-van den Bosch Judith, Clemens Ralf, Breuer Thomas
机构信息
Instituto Evandro Chagas, Secretaria de Vigilância em Saúde, Ministério da Saúde, Belém, Brazil.
出版信息
Clin Infect Dis. 2006 Aug 1;43(3):312-4. doi: 10.1086/505493. Epub 2006 Jun 23.
The association between rotavirus serotypes and severity is not well established. Analysis of a clinical trial conducted in Latin America points at more-severe disease associated with serotype G9. Thus, demonstration of efficacy against G9 will be an important asset of any rotavirus vaccine to be introduced into a Latin American country or any country where G9 has been shown to be prevalent.
轮状病毒血清型与疾病严重程度之间的关联尚未完全明确。一项在拉丁美洲开展的临床试验分析指出，血清型G9与更严重的疾病有关。因此，对于任何即将引入拉丁美洲国家或已证明G9流行的任何国家的轮状病毒疫苗而言，证明其对G9的有效性将是一项重要优势。
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